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Retinoid Receptor Expression and Its Correlation to Retinoid Sensitivity in Non - M3 Acute Myeloid Leukemia Blast Cells / Samah Mohamed Abd El Hamid ; Supervised Naila Abdelfattah Omran , Mervat Mohamed ElAnsary , Mervat Mohamed Wageh Mattar

By: Contributor(s): Language: Eng Publication details: Cairo : Samah Mohamed Abdelhamid , 2006Description: 214p : ill ; 25cmOther title:
  • التعبير عن مستقبل الريتينويد ودراسة مقدار حساسيته لمادة الريتينويد فى حالات سرطان الدم الميلويدى الحاد ما عدا ام3 [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (PH.D.) - Cairo University - Faculty Of Medicine - Department Of Clinical and Chemical Pathology Summary: RAR - receptor is expressed and up - regulated in response to ATRA in a good proportion of patients with AMLA considerable variability was noticed regarding the basal expression levels and the amplitude of up - regulationFAB subtypes and CD34 expression may influence the response to ATRA but other contributing factors should be consideredUp - regulation of RAR - ? receptor expression in AML was not associated with granulocytic maturationSince the retinoid protocols for non - M3 AML patients have drawn attention in the past years , the ability to express and up - regulate RAR - receptor in AML leukemic cells may be useful as predictive test during treatment with retinoids especially with the availability of real time PCR as a sensitive , specific , rapid and quantitative assay for RAR - receptor expressio
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Item type Current library Home library Call number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.07.Ph.D.2006.Sa.R. (Browse shelf(Opens below)) Not for loan 01010110045337000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.07.Ph.D.2006.Sa.R. (Browse shelf(Opens below)) Not for loan 01020110045337000

Thesis (PH.D.) - Cairo University - Faculty Of Medicine - Department Of Clinical and Chemical Pathology

RAR - receptor is expressed and up - regulated in response to ATRA in a good proportion of patients with AMLA considerable variability was noticed regarding the basal expression levels and the amplitude of up - regulationFAB subtypes and CD34 expression may influence the response to ATRA but other contributing factors should be consideredUp - regulation of RAR - ? receptor expression in AML was not associated with granulocytic maturationSince the retinoid protocols for non - M3 AML patients have drawn attention in the past years , the ability to express and up - regulate RAR - receptor in AML leukemic cells may be useful as predictive test during treatment with retinoids especially with the availability of real time PCR as a sensitive , specific , rapid and quantitative assay for RAR - receptor expressio

Issued also as CD

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