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Synthesis of polymer- inorganic hybrid anti-cancer drug nanosystem and evaluation of their anticancer potential /

Hadeel Aboubakr Mahmoud Kandeel

Synthesis of polymer- inorganic hybrid anti-cancer drug nanosystem and evaluation of their anticancer potential / تشييد نظام نانو مترى من بوليمرو عنصر غير عضوى محمل بعقار مضاد للسرطان وتقييم تاثيره كمضاد للسرطان Hadeel Aboubakr Mahmoud Kandeel ; Supervised Baheya Riyad , Mervat Elansary , Mohamed Ali Eldesouky - Cairo : Hadeel Aboubakr Mahmoud Kandeel , 2015 - 83 P. : charts , facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biochemistry

Background : Super paramagnetic nanoparticle can serve as a drug carrier in controolled drug delivery and targeted at cancer diagnostics and therapeutics .In this work the super paramagnetic iron oxide nanoparticles synthesized by co- precipitation method and the conjugate is made of iron oxide nanoparticles covalently bound with methotrexate (MTX) a chemotherapeutic drug that can targetmany cancer cells whose surfaces are overexpressed by folate receptors



Chitosan Drug targeting Magnetic iron oxide nanoparticles