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Design and synthesis of 2,4-disubstituted quinazolines and their biological evaluation as anti-infective agents /

Sarah Hamdy Megahed Ahmed

Design and synthesis of 2,4-disubstituted quinazolines and their biological evaluation as anti-infective agents / تصميم و تشييد مشتقات جديدة من 2و4ثنائى مستبدالات الكينازولين و تقييم قدرتها كمضادات للعدوى Sarah Hamdy Megahed Ahmed ; Supervised Ashraf H. Abadi , Mohammad Abdelhalim , Mostafa Hamed - Cairo : Sarah Hamdy Megahed Ahmed , 2016 - 102 Leaves ; 30cm

Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceulical Chemistry

Antibioties have an improtant role in the treatmant of many infectious diseases. The market is in an ever-growing demand for new antibioties that can address the emerging threat of antibiotic resistance. Many quinazoline derivatives possess different biological effects including anti-infective activities. Several 2,4 diaminoquinazoline derivatives were reported to have potent activity against MRSA. Moreover, it was found that several 2-thioguinazolin-4-one derivatives have dignificant activity against mycobocteria

2,4-disubstituted quinazolines Anti-infective agents Antibioties