MARC details
| 000 -LEADER |
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| fixed length control field |
02341cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
150221s2014 ua do f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.08.09.M.Sc.2014.Ma.P |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Maha Moussa Mahmoud Shouman |
| 245 14 - TITLE STATEMENT |
|---|
| Title |
The possible protective effect of certain natural products in experimentally induced nephrotoxicity in rats / |
| Statement of responsibility, etc. |
Maha Moussa Mahmoud Shouman ; Supervised Sanaa A. Kenawy , Amany I. Elbrairy , Rania M. Abdelsalam |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
إمكانية التأثير الوقائى لبعض المنتجات الطبيعية فى التسمم الكلوى المحدث تجريبيا فى الجرذان |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Maha Moussa Mahmoud Shouman , |
| Date of publication, distribution, etc. |
2014 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
159 P. : |
| Other physical details |
charts , photographs ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Nephrotoxicity is a major complication and a dose limiting factor for cisplatin therapy. Recent evidence suggests that inflammation and oxidative stress may contribute to the pathogenesis of cisplatin induced acute renal failure. A large number of natural products and dietary components have been evaluated as potential chemoprotective agents. The present study was performed to explore the effect of pretreatment with curcumin (60 mg / kg) and grape seed extract (200 mg / kg) either alone or in combination with valsartan (30 mg / kg) in cisplatin induced nephrotoxicity in rats. Blood samples were collected to measure renal function tests including serum level of creatinine (Cr) and blood urea nitrogen (BUN) as well as serum level of c- reactive protein (CRP), tumor necrosis factor alpha (TNF- Ü) and interleukin 10 (IL - 10). Furthermore, kidneys were excised for histological examination and for the measurement of oxidative stress biomarkers including renal contents of malondialdehyde MDA |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
|---|
| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Cisplatin |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Curcumin |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Grape seed extract |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Amany I. Elbrairy , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Rania M. Abdelsalam , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Sanaa A. Kenawy , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Samia |
| Reviser |
Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
