Development of mucoadhesive buccal delivery system for a corticosteroid drug / (Record no. 50571)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02050cam a2200313 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 150422s2014 ua h f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.08.M.Sc.2014.He.D |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Hend Ibrahim Shahin |
| 245 10 - TITLE STATEMENT | |
| Title | Development of mucoadhesive buccal delivery system for a corticosteroid drug / |
| Statement of responsibility, etc. | Hend Ibrahim Shahin ; Supervised Mahmoud M. Ghorab , Hussein O. Ammar |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تطوير نظام لاصق للمخاط الفموى لدواء كورتيكوستيرُويدى |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Hend Ibrahim Shahin , |
| Date of publication, distribution, etc. | 2014 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 219 P. : |
| Other physical details | facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The main objective of the thesis was to develop and evaluate mucoadhesive buccal film containing fluticasone propionate for management of severe erosive mouth lesions. The films were prepared by solvent casting technique using different polymeric blends. The prepared mucoadhesive films were subjected to extensive physicochemical evaluation, as well as studying their in-vitro drug release and mucoadhesion residence time which revealed acceptable drug content, release profiles and mucoadhesion time. The optimized formulations were subjected to DSC thermograms, XRD and the effect of storage studies. Finally, in vivo performance of the optimized formulations were evaluated in human volunteers by analysis of salivary drug concentration over 10 hrs where the pharmacokinetic parameters were calculated and compare to prepared mouthwash containing the same dose as in the mucoadhesive films |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Corticosteroids |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Fluticasone propionate |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Mucoadhesive buccal films |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hussein Osman Ammar , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mahmoud Mohamed Ghorab , |
| Relator term | |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.08.M.Sc.2014.He.D | 01010110065241000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.08.M.Sc.2014.He.D | 01020110065241000 | 22.09.2023 | CD - Rom | 65241.CD |