Evaluation of the therapeutic effect of whey proteins on the hepatotoxicity induced by paracetamol and alcohol Co-administration in rats / (Record no. 50972)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02480cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031229.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 150520s2014 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.09.Ph.D.2014.He.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Hesham Abdullah Helmy Eleiwa |
| 245 10 - TITLE STATEMENT | |
| Title | Evaluation of the therapeutic effect of whey proteins on the hepatotoxicity induced by paracetamol and alcohol Co-administration in rats / |
| Statement of responsibility, etc. | Hesham Abdullah Helmy Eleiwa ; Ezz Eldin Said Eldenshary , Somaia Ahmad Nada , Mohamed Farrag Elyamany |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تقييم بروتينات شرش اللبن لعلاج التسمم الكبدى المحدث بواسطة الباراسيتامول مع الكحول فى جزذان التجارب |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Hesham Abdullah Helmy Eleiwa , |
| Date of publication, distribution, etc. | 2014 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 174 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Hepatotoxicity induced by oral co-administration of paracetamol (APAP) (500 mg / kg) and alcohol (5 ml/ kg ) to each rat for two and four weeks .On the other hand, oral administration of whey protein isolate (WPI), alpha- lactalbumin (Ü-LA) and beta-lactoglobulin (Ý-LG) are used as therapeutic agents, in two dose levels (100 and 200 mg/kg) after induction of hepatotoxicity in both two and four weeks ,then liver tissue and blood sample collected. Oral administrated of APAP (500 mg / kg ) and alcohol (5 ml/ kg ) for two and four weeks increase in serum levels of alanine aminotransferase (ALT), and aspartate aminotransferase (AST). While, oral administration of WPI, Ü-LA and Ý-LG after APAP and alcohol resulted in reduction in serum AST and ALT activities , serum tumor necrosis factor- alpha (TNF- Ü) and hepatic lipid peroxidation marker malondialdehyde (MDA),while increase oxidative stress biomarkers (hepatic reduced glutathione (GSH) and superoxide dismutase (SOD) |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Co-administration |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Hepatotoxicity |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Paracetamol |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ezz Eldin Said Eldenshary , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Farrag Elyamany , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Somaia Ahmad Nada , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Soheir |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.09.Ph.D.2014.He.E | 01010110065612000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.09.Ph.D.2014.He.E | 01020110065612000 | 22.09.2023 | CD - Rom | 65612.CD |