Effect of insulin and phosphodiesterase type - 5 inhibitor (sildenafil) on aromatase level and uterine function in streptozotocin - induced diabetic female rats / (Record no. 51124)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02610cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031233.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 150531s2014 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.30.M.Sc.2014.Sa.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Safaa Mohammed Abdelwahab |
| 245 10 - TITLE STATEMENT | |
| Title | Effect of insulin and phosphodiesterase type - 5 inhibitor (sildenafil) on aromatase level and uterine function in streptozotocin - induced diabetic female rats / |
| Statement of responsibility, etc. | Safaa Mohammed Abdelwahab ; Supervised Alaa Eldin Amin Afifi , Hanan Abdelaziz Mubarak , Dina Sabry |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تأثير الإنسولين و العقار المثبط لإنزيم فوسفوداى إستريز٥ (السيلدنافيل) على مستوى الأروماتيز و وظائف الرحم فى إناث الفئران المصابة بداء السكرى الناجم عن إعطاء عقار الإستربتوزوتوسين |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Safaa Mohammed Abdelwahab , |
| Date of publication, distribution, etc. | 2014 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 141 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Physiology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Type I Diabetes Mellitus (DM) is associated with multiple reproductive abnormalities and hypoestrogenemia. This study aimed to assess the effect of diabetes on aromatase enzyme gene expression in ovarian and uterine tissues, as well as, its effect on the height of uterine contractions. Also, to identify the possible therapeutic effects of insulin and sildenafil on both the aromatase enzyme level and the height of uterine contractions. Fifty female rats divided into five groups, ten for each, Group I: normal control rats, Group II: untreated streptozotocin-induced diabetic rats, Group III: insulin - treated diabetic, Group IV: phosphodiesterase type 5 inhibitor (PDE5i)-sildenafil-treated diabetic rats and group V: Combined PDE5i (sildenafil) and insulin - treated diabetic rats. Fasting glucose, fasting insulin and estrogen were measured in serum. Aromatase enzyme gene expression was measured in both ovarian and uterine tissues. Peak heights of spontaneous uterine contractions were recorded |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Aromatase enzyme |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Diabetes |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Uterine contraction |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Alaa Eldin Amin Afifi , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dina Sabry , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hanan Abdelaziz Mubarak , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.30.M.Sc.2014.Sa.E | 01010110065691000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.30.M.Sc.2014.Sa.E | 01020110065691000 | 22.09.2023 | CD - Rom | 65691.CD |