Study of the effect of linezolid alone and in combination with other antibiotics on methicillin resistant staphylococcus aureus electron microscope and time kill study / (Record no. 59721)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02946cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031647.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170207s2016 ua h f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.19.Ph.D.2016.Mo.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Moushira Ali Badawi Masoud |
| 245 10 - TITLE STATEMENT | |
| Title | Study of the effect of linezolid alone and in combination with other antibiotics on methicillin resistant staphylococcus aureus electron microscope and time kill study / |
| Statement of responsibility, etc. | Moushira Ali Badawi Masoud ; Supervised Hamida Mohamed Abdelhamid Gohar , Hoda Ahmed Yehia Abdalla , Nadia Mohammed Hassan Madany |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة بالميكروسكوب الإليكترونى و اختبار الوقت اللازم للقتل على ميكروب البكتيريا العنقودية المقاومة للمثيسيللين باستخدام مضاد اللاينيزوليد بمفرده و بالإضافة إلى مضادات حيويه اخرى |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Moushira Ali Badawi Masoud , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 130 P. : |
| Other physical details | facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Microbiology and Immunology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The prevalence of methicillin resistant Staphyloccoccus. aureus (MRSA) strains has presented a new challenge in antimicrobial medication. Linezolid is a new drug with potent activity on Gram positive pathogens such as MRSA. The aim of the study was to investigate the in vitro activity of linezolid alone and in combination with imipenem, vancomycin or rifampicin to determine the most active therapy against MRSA strains linezolid may be combined with other antimicrobial agents in order to provide broad-spectrum coverage, prevent the emergence of resistant mutants, and obtain a synergy between both antimicrobial agents. Twenty clinical MRSA strains were isolated from patients admitted to inpatient departments and outpatient clinics of theodor bilharz research Institute. Standard strain MRSA ATCC 43300 was included as a control. The MICs of MRSA strains to linezolid, vancomycin, imipenem and rifampicin were evaluated using E test. Time kill curve experiments were used to assess the in vitro activity of linezolid (at 8x MIC) alone and in combination with imipenem (at 32x MIC), vancomycin or rifampicin (at 8x MIC). Scanning and transmission electron microscopy were performed to compare bacterial morphological alterations owing to the different combinations |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Imipenem |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Linezolid |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | MRSA |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hamida Mohamed Abdelhamid Gohar , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hoda Ahmed Yehia Abdalla , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nadia Mohammed Hassan Madany , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.19.Ph.D.2016.Mo.S | 01010110071031000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.19.Ph.D.2016.Mo.S | 01020110071031000 | 22.09.2023 | CD - Rom | 71031.CD |