Pharmacological study of the possible protective effect of barley and green tea against N-dimethylnitrosamine induced carcinogenesis in rats / (Record no. 64267)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03086cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031904.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 171226s2017 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.09.M.Sc.2017.Sa.P |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Sara Belal Ahmed |
| 245 10 - TITLE STATEMENT | |
| Title | Pharmacological study of the possible protective effect of barley and green tea against N-dimethylnitrosamine induced carcinogenesis in rats / |
| Statement of responsibility, etc. | Sara Belal Ahmed ; Supervised Hekma A. Abdellatif , Afaf A. Ain Shoka , Mahmoud S.S. Arbid |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة دوائية للتاثير الوقائي المحتمل للشعير والشاي الأخضر في السرطان المحدث باستخدام الداي ميثيل نيتروزامين في الجردان |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Sara Belal Ahmed , |
| Date of publication, distribution, etc. | 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 186 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Objectives: The aim of the present study is to investigate the effects of the green tea, barley anddoxorubicin and their combination on some changes produced by experimentally induced cancer by N-dimethylnitrosamine (DMN) in rats. Methods: cancerwasinduced in rats byadministration of DMN (25 mg/kg) orally daily for 6 weeks. Group1: given saline orally and servedas normal control. Group2: received DMN for 6 weeks and served as cancer control. Group3-4: given green tea extract (1 g/ kg) and barley extract (625 mg/ kg), orally for 4 weeks. Group 5-8: all ratsgiven DMNfor 6 weeks then treated with green tea, barley, doxorubicin and their combination of green tea,barley and doxorubicin for 4 weeks starting from the second week of DMN. Results: DMN provoked kidney and liver apoptosis as evidenced byelevation of kidney and liver functions, decrease in serum calcium level, elevation of tumor marker alpha-fetoprotein(AFP), ferritin and lactate dehydrogenase (LDH). DMN group had higher kidney nitric oxide(NO) and malondialdehyde (MDA) contents and lower superoxide dismutase (SOD), as well as it inducedinflammation, apoptosis and caspase-3 expression. Green, barley and their combination improved thebiochemical and histopathological changes in kidney and liver induced by DMN. Conclusion: This study indicates thetherapeutic effect of green tea, barley against DMN-induced kidney and liver apoptosis. Interestingly, ourresults exhibited that doxorubicin conjugated with green tea and barley increased renal and hepatic protectionactivity and may decrease systemic toxicity of doxorubicin when administered in high dose |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Cancer |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | kidney |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Liver |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Afaf A. Ain Shoka , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hekma A. Abdellatif , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mahmoud S. S. Arbid , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.09.M.Sc.2017.Sa.P | 01010110073898000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.09.M.Sc.2017.Sa.P | 01020110073898000 | 22.09.2023 | CD - Rom | 73898.CD |