MARC details
| 000 -LEADER |
|---|
| fixed length control field |
02733cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
180515s2017 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.08.05.M.Sc.2017.Na.D |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Naira Ahmed Farid Mohammed |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Development and validation of analytical methods for the determination of some drugs affecting blood coagulation / |
| Statement of responsibility, etc. |
Naira Ahmed Farid Mohammed ; Supervised Ramzia Ismail Ibrahim Elbagary , Nadia Fayek Youssef , Ehab Farouk Hassan Elkady |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
تطويرِ و تقييمِ طرق تحليليةِ لتقديرِ بعضِ الأدويةِ المؤثرة علىِ تجلط الدم |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Naira Ahmed Farid Mohammed , |
| Date of publication, distribution, etc. |
2017 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
220 P. : |
| Other physical details |
charts ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
The health and the safety of pharmaceutical products consumers are protected by the national control laboratories. Prior the pharmaceutical product is approved to the market; Several tests must be applied to ensure that these products meet the accepted standard of quality, efficacy and safety. However, time consuming method is usually stood as barrier to achieve fast results. This study concerns developing fast, simple, cheap, accurate and accessible analytical methods for the determination of selected anticoagulant drugs. Using reversed phase high performance liquid chromatography, stability study of tirofiban hydrochloride was studied. Moreover, tyrosine the synthetic starting material of tirofiban hydrochloride could be quantified from 1 æg mL-1. Tirofiban hydrochloride, rivaroxaban and apixaban ternary mixture could be determined accurately. Then, spectrofluorimetric methods were introduced for the determination of tirofiban hydrochloride and apixaban. Also, chemometric multivariate calibration techniques namely; classical least squares, principle component regression and partial least square regression were used for the simultaneous determination of tirofiban hydrochloride and tyrosine. Artificial neural networks were also applied to UV spectrophotometric data for the simultaneous determination of tirofiban hydrochloride and tyrosine |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
|---|
| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Anticoagulant drugs |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Chemometry |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
High performance liquid chromatography |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Ehab Farouk Hassan Elkady , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Nadia Fayek Youssef , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Ramzia Ismail Ibrahim Elbagary , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Samia |
| Reviser |
Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
