Analytical study of some drugs used in treatment of diabetes / (Record no. 72871)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02422cam a2200337 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032328.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190716s2019 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.05.Ph.D.2019.Mi.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Michael Gamal Fawzy Abdelmalek |
| 245 10 - TITLE STATEMENT | |
| Title | Analytical study of some drugs used in treatment of diabetes / |
| Statement of responsibility, etc. | Michael Gamal Fawzy Abdelmalek ; Supervised Bahia Abbas Moussa , Marianne Alphonse Mahrouse |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دارسة تحليلية لبعض الأدوية المستخدمة فى علاج مرض السكر |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Michael Gamal Fawzy Abdelmalek , |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 170 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | This thesis is concerned with the analysis of fourantidiabeticdrugs, Canagliflozin (CAG) and Empagliflozin (EMG) (sodium glucose co-transporter II inhibitors), Linagliptin (LIG) (Dipeptidyl peptidase IV inhibitor) and Metformin HCl (MEF) (Biguanide agent).The selected drugs were analyzed in the pure form, in laboratory prepared mixtures, in a dosage form or in the biological fluid.Ratio difference coupled with modified isosbestic point and amplitude modulation spectrophotometric methodswere proposed for the simultaneous determination of CAG and MEF.While EMG and LIG were estimated simultaneously by applying ratio subtraction coupled with extended ratio subtraction spectrophotometric methods. Also chemometric- assisted FTIR spectrophotometric method was applied for the determination of (EMG/LIG) in binary mixture. A HPLC-MS/MS method was developed for the simultaneous quantification of LIGand MEF in spiked human plasma coupled with solid phase extraction using alogliptin as an internal standard. The developed method was applied for the evaluation of potential pharmacokinetic interactions between the two drugs in healthy human volunteers |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Canagliflozin |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Empagliflozin |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Linagliptin |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bahia Abbas Moussa , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Marianne Alphonse Mahrouse , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.05.Ph.D.2019.Mi.A | 01010110078711000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.05.Ph.D.2019.Mi.A | 01020110078711000 | 22.09.2023 | CD - Rom | 78711.CD |