MARC details
| 000 -LEADER |
|---|
| fixed length control field |
02496cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
190902s2019 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.08.07.Ph.D.2019.Ri.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Riham Adel Elshiekh |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Assessment of some medicinal plants for treatment of obesity / |
| Statement of responsibility, etc. |
Riham Adel Elshiekh ; Supervised Mohamed S. Hifnawy , Essam A. Abdelsattar , Dalia A. Almahdy |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
تقييم بعض النباتات الطبية لعلاج السمنة |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Riham Adel Elshiekh , |
| Date of publication, distribution, etc. |
2019 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
195 P. : |
| Other physical details |
charts , facsimiles ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmacognosy |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
The total methanolic and aqueous extracts of five plants (viz: Caralluma quadrangula, Caralluma tuberculata, Hibiscus shizopetalous, Hibiscus sabdariffa (white variety) and Solenostemma argel) were tested for their inhibitory activity against pancreatic lipase, Ü-amylase and Ü-glucosidase enzymes, along with their anti-oxidant potential via two different complementary methods; DPPH (1, 1-Diphenyl-2-picrylhydrazyl) radical scavenging activity and iron reducing power assays. The plants extracts were also estimated quantitatively for their total phenolic, flavonoid, tannin and steroidal contents. The results showed that Solenostemma argel was the most active among the selected plants. An optimized extraction method was developed for S. argel based on its enzyme inhibitory activity to ensure maximum biological activity. The methylene chloride and n-butanol fractions, in addition to, seven isolated compounds viz: sterols, pregnane glycoside and flavonoid aglycones and glycosides from S. argel were further evaluated. In-vivo biological study revealed that S. argel is a promising Egyptian natural drug, rich in pregnane glycosides, and could be considered a new therapeutic candidate targeting obesity. The ethanolic extract was also standardized using LC{u2013}MS analysis for its content of stemmoside C |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
|---|
| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Solenostemma argel |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Ü-Amylase |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Ü-Glucosidase |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Dalia A. Almahdy , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Essam A. Abdelsattar , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mohamed S. Hifnawy , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Asmaa |
| Reviser |
Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
