Evaluation of serum level of phosphodiesterase-4 enzyme in alopecia areata patients / (Record no. 75560)
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000 -LEADER | |
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fixed length control field | 02369cam a2200325 a 4500 |
003 - CONTROL NUMBER IDENTIFIER | |
control field | EG-GiCUC |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 191130s2019 ua dh f m 000 0 eng d |
040 ## - CATALOGING SOURCE | |
Original cataloging agency | EG-GiCUC |
Language of cataloging | eng |
Transcribing agency | EG-GiCUC |
041 0# - LANGUAGE CODE | |
Language code of text/sound track or separate title | eng |
049 ## - LOCAL HOLDINGS (OCLC) | |
Holding library | Deposite |
097 ## - Thesis Degree | |
Thesis Level | M.Sc |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
Classification number | Cai01.11.10.M.Sc.2019.No.E |
100 0# - MAIN ENTRY--PERSONAL NAME | |
Personal name | Nour Mohamed Bakr Elzawahry |
245 10 - TITLE STATEMENT | |
Title | Evaluation of serum level of phosphodiesterase-4 enzyme in alopecia areata patients / |
Statement of responsibility, etc. | Nour Mohamed Bakr Elzawahry ; Supervised Rehab Mohamed Sobhi , Eman Sanny Zaki , Olfat Shaker |
246 15 - VARYING FORM OF TITLE | |
Title proper/short title | تقييم مستوى الفوسفو داى أستريز- 4 بالدم فى مرضى الثعلبة |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Place of publication, distribution, etc. | Cairo : |
Name of publisher, distributor, etc. | Nour Mohamed Bakr Elzawahry , |
Date of publication, distribution, etc. | 2019 |
300 ## - PHYSICAL DESCRIPTION | |
Extent | 91 P. : |
Other physical details | charts , facsimiles ; |
Dimensions | 25cm |
502 ## - DISSERTATION NOTE | |
Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venerology |
520 ## - SUMMARY, ETC. | |
Summary, etc. | Background: Alopecia areata (AA) is a noncicatricial alopecia affecting any hair-bearing area and is considered to be an organ-specific autoimmune disease mediated by T lymphocytes directed to hair follicles.The exact etiology of AA remains unclear but genetic and environmental factors have been shown to trigger the initiation of the disease.Concerning the etiology and pathogenesis of AA; innate and acquired immunity involvement in the pathogenesis, as well as IFNÞ-driven immune response, including IFNÞ, IFNÞ-induced chemokines and cytotoxic CD8 T cells.The hair follicle has a low level of major histocompatibility complex making it an immune-privileged site where CD8+ T lymphocytes target the follicle{u2019}s bulb resulting from a breakdown in immune privilege which leads to induction of the hair follicle to undergo apoptosis that results in inhibition of cell division within the hair matrix and of hair shaft production.Phosphodiesterases (PDEs) are enzymes that break down cyclic adenosine monophosphate (cAMP) or cyclic guanosine monophosphate (cGMP) and they demonstrate activity in all cells in the body |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
Additional physical form available note | Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Alopecia Areata |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | PDE4 |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | PDE4 Inhibitors |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Eman Sanny Zaki , |
Relator term | |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Olfat Shaker , |
Relator term | |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Rehab Mohamed Sobhi , |
Relator term | |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
Cataloger | Nazla |
Reviser | Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
Cataloger | Shimaa |
Reviser | Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Source of classification or shelving scheme | Dewey Decimal Classification |
Koha item type | Thesis |
Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
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Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.10.M.Sc.2019.No.E | 01010110080225000 | 22.09.2023 | Thesis | ||
Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.10.M.Sc.2019.No.E | 01020110080225000 | 22.09.2023 | CD - Rom | 80225.CD |