header
Image from OpenLibrary

Evaluation of serum level of phosphodiesterase-4 enzyme in alopecia areata patients / Nour Mohamed Bakr Elzawahry ; Supervised Rehab Mohamed Sobhi , Eman Sanny Zaki , Olfat Shaker

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Nour Mohamed Bakr Elzawahry , 2019Description: 91 P. : charts , facsimiles ; 25cmOther title:
  • تقييم مستوى الفوسفو داى أستريز- 4 بالدم فى مرضى الثعلبة [Added title page title]
Subject(s): Available additional physical forms:
  • Issued also as CD
Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venerology Summary: Background: Alopecia areata (AA) is a noncicatricial alopecia affecting any hair-bearing area and is considered to be an organ-specific autoimmune disease mediated by T lymphocytes directed to hair follicles.The exact etiology of AA remains unclear but genetic and environmental factors have been shown to trigger the initiation of the disease.Concerning the etiology and pathogenesis of AA; innate and acquired immunity involvement in the pathogenesis, as well as IFNÞ-driven immune response, including IFNÞ, IFNÞ-induced chemokines and cytotoxic CD8 T cells.The hair follicle has a low level of major histocompatibility complex making it an immune-privileged site where CD8+ T lymphocytes target the follicle{u2019}s bulb resulting from a breakdown in immune privilege which leads to induction of the hair follicle to undergo apoptosis that results in inhibition of cell division within the hair matrix and of hair shaft production.Phosphodiesterases (PDEs) are enzymes that break down cyclic adenosine monophosphate (cAMP) or cyclic guanosine monophosphate (cGMP) and they demonstrate activity in all cells in the body
Tags from this library: No tags from this library for this title. Log in to add tags.
Star ratings
    Average rating: 0.0 (0 votes)
Holdings
Item type Current library Home library Call number Copy number Status Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.10.M.Sc.2019.No.E (Browse shelf(Opens below)) Not for loan 01010110080225000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.10.M.Sc.2019.No.E (Browse shelf(Opens below)) 80225.CD Not for loan 01020110080225000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venerology

Background: Alopecia areata (AA) is a noncicatricial alopecia affecting any hair-bearing area and is considered to be an organ-specific autoimmune disease mediated by T lymphocytes directed to hair follicles.The exact etiology of AA remains unclear but genetic and environmental factors have been shown to trigger the initiation of the disease.Concerning the etiology and pathogenesis of AA; innate and acquired immunity involvement in the pathogenesis, as well as IFNÞ-driven immune response, including IFNÞ, IFNÞ-induced chemokines and cytotoxic CD8 T cells.The hair follicle has a low level of major histocompatibility complex making it an immune-privileged site where CD8+ T lymphocytes target the follicle{u2019}s bulb resulting from a breakdown in immune privilege which leads to induction of the hair follicle to undergo apoptosis that results in inhibition of cell division within the hair matrix and of hair shaft production.Phosphodiesterases (PDEs) are enzymes that break down cyclic adenosine monophosphate (cAMP) or cyclic guanosine monophosphate (cGMP) and they demonstrate activity in all cells in the body

Issued also as CD

There are no comments on this title.

to post a comment.