Biochemical studies on the relation between tamoxifen, nano-nutrients and some bioactive components and gene expression in experimental breast cancer / (Record no. 77182)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02783cam a2200337 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032540.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200811s2020 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.02.Ph.D.2020.Di.B |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Dina Mostafa Mohammed Mohammed |
| 245 10 - TITLE STATEMENT | |
| Title | Biochemical studies on the relation between tamoxifen, nano-nutrients and some bioactive components and gene expression in experimental breast cancer / |
| Statement of responsibility, etc. | Dina Mostafa Mohammed Mohammed ; Supervised Abdou Osman Abdelhamid , Afaf Ezzat Abbas |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسات بيوكيميائية عن العلاقة بين التاموكسفين: المغذيات النانو وبعض المركبات النشطة حيويا والتعبير الجينى فى سرطان الثدى التجريبي |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Dina Mostafa Mohammed Mohammed , |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 289 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Biochemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | This work had been carried out to study converting drug (Tamoxifen), some nutrients (yeast) and bioactive compounds (Silymarin and Isoflavone) to nanoparticles and study their different effects in nano and normal scale on gene expression. Encourage the use of nanotechnology to limit the development and spread of breast cancer and the inhibitory effect of them on development of toxic material of mammary tumor for 180 days against with a single oral dose of (25 mg/kg) 7,12-dimethylbenz[a]anthracene (DMBA) in female rats. The body weight and food consumption will be examined. Upon the completion of the study, the histopathological studies on the breast tissues will be performed. The therapeutic and protective effects of these compounds in nano and normal scale will be evaluated using the appropriate parameters to determine the level of several chemicals related to oxidative damage (8-OHdG, Lipid Peroxide, TAC), Apoptosis, Plasma Estrogen and ErbB-2 in the blood samples. Also, the gene expression of ErbB-2 will be investigated in the blood samples. Finally, all the experimental results evaluated, tabulated and statistically analyzed. In conclusion, Breast cancer is highly curable if diagnosed with nutrients or medications whether in their normal or nano particles form at an early stage |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Bioactive Components |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Breast Cancer |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Experimental Rats |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Abdou Osman Abdelhamid , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Afaf Ezzat Abbas , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.02.Ph.D.2020.Di.B | 01010110081185000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.02.Ph.D.2020.Di.B | 01020110081185000 | 22.09.2023 | CD - Rom | 81185.CD |