MARC details
| 000 -LEADER |
|---|
| fixed length control field |
02968cam a2200313 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
200825s2020 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.11.28.M.Sc.2020.Pe.C |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Peter Atef Samy |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Clinical significance of matrix metalloproteinase-3 in juvenile systemic lupus erythematosus patients / |
| Statement of responsibility, etc. |
Peter Atef Samy ; Supervised Samia Salah Eldin Mahmoud , Mervat Mamdooh Khorshied |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
الدلالة الاكلينيكية لانزيم ماتريكس ميتالوبروتيناز-3 فى الأطفال المصابون بمرض الذئبة الحمراء |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Peter Atef Samy , |
| Date of publication, distribution, etc. |
2020 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
135 P. : |
| Other physical details |
charts , facsimile ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Introduction: Childhood systemic lupus erythematosus (cSLE) is a multisystem disorder with variety of autoantibodies formation. Score of damage index (SDI) can represents the disease effect in multiple systems, but new markers can be used for further assessment and evaluation of disease activity of cSLE. Objective:The present study was conducted to estimate and evaluate Matrix Metalloproteinase-3 (MMP-3) in disease activity of cSLE and its correlation with SDI. Patients and methods:This case control study was conducted on 45 patients with juvenile systemic lupus erythematosus (JSLE) who were diagnosed according to SLICC 2012 criteria (Petri, 2012), and was recruited from the Rheumatology Clinic of children hospital, Cairo University. In addition to 45 healthy age and sex matched control group who were recruited from other clinics at Paediatric Hospital in a period from August 2019 to October 2019. All the included children were subjected to full history taking, complete physical examination, and investigations including; Complete blood picture, serum electrolytes, kidney functions, liver functions, complements, autoantibodies.Disease activity scoring using SDI was done and measurement of MMP-3. Results:There is statistically significant difference regarding level of MMP-3 between patients with different manifestations of SLE throughout course of the disease. There is statistically significant correlation between level of MMP-3 and score of damage index with p value 0.000. Our study revealed statistically significant difference regarding levels of MMP-3 in patients with and patients without neurological manifestations of SLE throughout course of the disease with P-value=0.000 |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
|---|
| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Childhood |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Disease activity |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Systemic lupus Erythematosus |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mervat Mamdooh Khorshied , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Samia Salah Eldin Mahmoud , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Shimaa |
| Reviser |
Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
