Serum soluble interleukin–2 receptor alpha and rantes chemokine as potential biomarkers for Covid–19 infection / by Nada Waheed Ahmed Radwan ; Supervised by Prof. Dr. Dalia Ahmed Aly Labib, Prof. Dr. Rasha Mohamad Hosny Shahin.

By:

Nada Waheed Ahmed Radwan [preparation.]

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Material type: Text

TextLanguage: English Summary language: English, Arabic Producer: 2022Description: 102 pages : Illustrations ; 25 cm. + CDContent type:

text

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Unmediated

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volume

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مستوى مستقبلات IL-2 الذائبة و كيموكين RANTES فى الدم كمؤشرات حيوية لعدوى فيروس كورونا المستجد [Added title page title]

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615.37 21

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Dissertation note: Thesis (M.Sc.)-Cairo University, 2022. Summary: The COVID 19 Pandemic has been a global emergency caused by the outbreak of SARS-CoV2 virus in Wuhan, Hubei, China in November 2019. The disease is characterized by acute respiratory distress among other symptoms produced by immune system disturbance and cytokine storm. Objective: To determine the serum level of soluble IL-2Ra and RANTES in COVID 19 patients and compare with healthy controls as well as detect correlation with disease severity. Methods: A case-control study was conducted on 60 patients with a positive nasopharyngeal swab tested by RealTime PCR for SARS- CoV2 admitted to isolation wards of Kasr Alainy Hospitals and COVID 19 outpatient clinics, and 25 healthy controls to measure serum levels of soluble IL-2Ra and RANTES using Enzyme Linked Immunosorbent Assay. Results: The results revealed no statistically significant difference in serum levels of soluble IL-2Ra and RANTES between patients and healthy controls, neither was there a difference in serum levels of both parameters between severe and non-severe cases of COVID 19.Summary: تحديد مستوى مصل IL-2Ra القابل للذوبان و RANTES في مرضى COVID 19 ومقارنتها مع الضوابط الصحية وكذلك الكشف عن الارتباط مع شدة المرض. الطرق: أجريت دراسة الحالات والشواهد على 60 مريضا يعانون من تم اختبار مسحة البلعوم الأنفي الإيجابية بواسطة RealTime PCR لمرض السارس- تم إدخال CoV2 إلى أجنحة العزل بمستشفيات القصر العيني و عيادات خارجية لكوفيد 19 و25 مراقبة صحية للقياس مستويات مصل IL-2Ra و RANTES القابلة للذوبان باستخدام الإنزيم المرتبط مقايسة الامتصاص المناعي.

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Item type	Current library	Home library	Call number	Status	Barcode
Thesis	قاعة الرسائل الجامعية - الدور الاول	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.11.07.M.Sc.2022.Na.S (Browse shelf(Opens below))	Not for loan	01010110087547000

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Previous	Cai01.11.07.M.Sc.2021.Su.R Role of ESR1 and FTO genetic variants on weight loss and glycemic control in obese patients undergoing bariatric surgery /	Cai01.11.07.M.Sc.2021.Ya.E Expression of NKp30 in de novo acute myeloid leukemia patients and its Impact on prognosis /	Cai01.11.07.M.Sc.2021.Ya.E Expression of NKp30 in de novo acute myeloid leukemia patients and its Impact on prognosis /	Cai01.11.07.M.Sc.2022.Na.S Serum soluble interleukin–2 receptor alpha and rantes chemokine as potential biomarkers for Covid–19 infection /	Cai01.11.07.M.Sc.2022.Ro.S. Study of trail (tnfsf10) and tl1a (tnfsf15) gene variants in systemic lupus erythematosus /	Cai01.11.07.M.Sc.2023.Ay.I Impact of ACE2 gene on the susceptibility of COVID-19 infection for De novo Acute Myeloid Leukaemia/	Cai01.11.07.M.Sc.2023.Ha.S Study of Potential Association Of PARP1 And DNMT3B Genes Expression With Incic And Prognosis Of Acute Myeloid Leukemia/	Next

Thesis (M.Sc.)-Cairo University, 2022.

Bibliography: pages 88-100.

The COVID 19 Pandemic has been a global
emergency caused by the outbreak of SARS-CoV2 virus in Wuhan,
Hubei, China in November 2019. The disease is characterized by
acute respiratory distress among other symptoms produced by
immune system disturbance and cytokine storm.
Objective: To determine the serum level of soluble IL-2Ra and
RANTES in COVID 19 patients and compare with healthy controls
as well as detect correlation with disease severity.
Methods: A case-control study was conducted on 60 patients with
a positive nasopharyngeal swab tested by RealTime PCR for SARS-
CoV2 admitted to isolation wards of Kasr Alainy Hospitals and
COVID 19 outpatient clinics, and 25 healthy controls to measure
serum levels of soluble IL-2Ra and RANTES using Enzyme Linked
Immunosorbent Assay.
Results: The results revealed no statistically significant difference
in serum levels of soluble IL-2Ra and RANTES between patients
and healthy controls, neither was there a difference in serum levels
of both parameters between severe and non-severe cases of COVID
19.

تحديد مستوى مصل IL-2Ra القابل للذوبان و RANTES في مرضى COVID 19 ومقارنتها مع الضوابط الصحية وكذلك الكشف عن الارتباط مع شدة المرض.
الطرق: أجريت دراسة الحالات والشواهد على 60 مريضا يعانون من تم اختبار مسحة البلعوم الأنفي الإيجابية بواسطة RealTime PCR لمرض السارس-
تم إدخال CoV2 إلى أجنحة العزل بمستشفيات القصر العيني و عيادات خارجية لكوفيد 19 و25 مراقبة صحية للقياس مستويات مصل IL-2Ra و RANTES القابلة للذوبان باستخدام الإنزيم المرتبط مقايسة الامتصاص المناعي.

Issues also as CD.

Text in English and abstract in Arabic & English.

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