Analytical studies on some marine toxins as a source of bioactive compounds / Mohamed Abou El - Abbas Embaby ; supervised Mahmoud Sabri Rizk , Ahmad Mahmoud Farag , Mohamed Nasr El - Deen Gomaa
Language: Eng Publication details: Cairo : Mohamed Abou El - Abbas Embaby Ibrahim , 2006Description: 135L : ill ; 30cmOther title:- دراسات تحليلية على بعض السموم البحرية كمصدر لمواد ذات نشاط بيولوجى [Added title page title]
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قاعة الرسائل الجامعية - الدور الاول | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.12.08.Ph.D.2006.Mo.A. (Browse shelf(Opens below)) | Not for loan | 01010110045204000 | |
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مخـــزن الرســائل الجـــامعية - البدروم | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.12.08.Ph.D.2006.Mo.A. (Browse shelf(Opens below)) | Not for loan | 01020110045204000 |
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Thesis (PH.D.) - Cairo University - Faculty Of Science - Department Of Analytical Chemistry
The present study has been carried out to detect the presence of low molecular weight bioactive compound (s) in the extract of some marine invertebrates collected from the Red Sea environmentThe crude extracts of the collected samples were subjected to different bioassay techniques such as mouse bioassay , brine shrimp , antimicrobial , antifungal , antiviral and Acetylcholine esterase inhibitionThe chemical studies of the Gyrostoma helianthus lead to isolation of two toxic fractions with two different modes of actionThe first toxic fraction inhibited the activity of Acetylcholine esterase and the second toxic fraction was k+potassium channel blockerThe bioactive compound (AchE inhibitor) was isolated in a pure form using HPLC and its chemical structure was elucidated using different spectroscopic techniquesThe toxicokinetics of the AchE inhibitor isolated bioactive compound was studie
Issued also as CD
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