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Methylation framework of cell cycle gene inhibitor p16 INK4A in hepatocellular carcinoma patients / Hany Ahmed Fouad Elghobary ; Supervised Fatma Ahmed Elmougy , Nabil Mostafa Khalil Elkady , Sahar Abdelatty Sharaf

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Hany Ahmed Fouad Elghobary , 2012Description: 168P. : charts , facsimiles ; 25cmOther title:
  • فى مرضى سرطان الخلايا الكبدية p16INK4A ميثلة الجين المثبط للدورة الخلوية جين ال [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology Summary: Hepatocellular carcinoma ( HCC ) is currently the fifth most common solid tumor worldwide and the third leading cause of cancer related death . The tumor suppressor gene p16 INK4A is located on chromosome 9p21 and encodes the p16 protein , which binds selectively to CDK4 to inhibit activation of the CDK4 / cyclin D complex in the G1 phase . Inactivation of this gene which normally inhibits progression to the G1 phase of the cell cycle is involved in the initiation of tumors
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.07.Ph.D.2012.Ha.M (Browse shelf(Opens below)) Not for loan 01010110058613000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.07.Ph.D.2012.Ha.M (Browse shelf(Opens below)) 58613.CD Not for loan 01020110058613000

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology

Hepatocellular carcinoma ( HCC ) is currently the fifth most common solid tumor worldwide and the third leading cause of cancer related death . The tumor suppressor gene p16 INK4A is located on chromosome 9p21 and encodes the p16 protein , which binds selectively to CDK4 to inhibit activation of the CDK4 / cyclin D complex in the G1 phase . Inactivation of this gene which normally inhibits progression to the G1 phase of the cell cycle is involved in the initiation of tumors

Issued also as CD

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