Real - time PCR assay of VKORC1 and CYP2C9 gene polymorphisms that affect warfarin response / Sherif Mofeed Megalla Ekladious ; Supervised Hazem Elsayed Abouyoussef , Sahar Abdelatty Sharaf , Marianne Samir Makboul

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Sherif Mofeed Megalla Ekladious

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TextLanguage: English Publication details: Cairo : Sherif Mofeed Megalla Ekladious , 2012Description: 127P. : charts , facsimiles ; 25cmOther title:

استخدام تفاعل البلمرة المتسلسل فى الزمن الحقيقى لاكتشاف الأشكال الجينية للجين CYP2C9والجينVKORC1 اللذان يؤثران على الاستجابة لدواء الوارفارين [Added title page title]

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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology Summary: Warfarin is a commonly used oral anticoagulant with a narrow therapeutic index and various genetic and clinical factors that influence interpatient variability in dose requirements . This study investigated the impact of genetic and nongenetic factors on warfarin dose requirements in Egyptians . DNA was extracted from 50 patients taking warfarin for more than 1 year and genotyped for VKORC1 (1173 C> T) , CYP2C9 *3 (1075 C>)gene polymorphisms using SYBR Green - based multiplex allele - specific PCR

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Item type	Current library	Home library	Call number	Copy number	Status	Date due	Barcode
Thesis	قاعة الرسائل الجامعية - الدور الاول	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.11.07.Ph.D.2012.Sh.R (Browse shelf(Opens below))		Not for loan		01010110058757000
CD - Rom	مخـــزن الرســائل الجـــامعية - البدروم	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.11.07.Ph.D.2012.Sh.R (Browse shelf(Opens below))	58757.CD	Not for loan		01020110058757000

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Previous	Cai01.11.07.Ph.D.2012.Re.I The impact of CYP2C9*3 and calumenin genetic polymorphisms on warfarin dose requirements /	Cai01.11.07.Ph.D.2012.Re.I The impact of CYP2C9*3 and calumenin genetic polymorphisms on warfarin dose requirements /	Cai01.11.07.Ph.D.2012.Sh.R Real - time PCR assay of VKORC1 and CYP2C9 gene polymorphisms that affect warfarin response /	Cai01.11.07.Ph.D.2012.Sh.R Real - time PCR assay of VKORC1 and CYP2C9 gene polymorphisms that affect warfarin response /	Cai01.11.07.Ph.D.2013.Ah.M Mex efflux pumps in MDR pseudomonas aeruginosa : Risk factors and detection /	Cai01.11.07.Ph.D.2013.Ah.M Mex efflux pumps in MDR pseudomonas aeruginosa : Risk factors and detection /	Cai01.11.07.Ph.D.2013.Al.G Glypican 3 as a novel marker for Hepatocellular carcinoma /	Next

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology

Warfarin is a commonly used oral anticoagulant with a narrow therapeutic index and various genetic and clinical factors that influence interpatient variability in dose requirements . This study investigated the impact of genetic and nongenetic factors on warfarin dose requirements in Egyptians . DNA was extracted from 50 patients taking warfarin for more than 1 year and genotyped for VKORC1 (1173 C> T) , CYP2C9 *3 (1075 C>)gene polymorphisms using SYBR Green - based multiplex allele - specific PCR

Issued also as CD

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