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Formulation and biopharmaceutical evaluation of an anti schizophrenic drug / Nermeen Adel Ahmed Elkasabgy ; Supervised Galal Elmahrouk , Mona Hassan Abouleinien

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Nermeen Adel Ahmed Elkasabgy , 2012Description: 284 P. : charts , facsimiles ; 25cmOther title:
  • صياغة و تقييم بيوصيدلى لعقار معالج لفصام الشخصية [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics Summary: Olanzapine is an effective antipsychotic drug used for the treatment of positive and negative symptoms of schizophrenia. But, it suffers from extensive first-pass metabolism in the liver to inactive metabolites, resulting in a poor oral bioavailability of nearly 60%. Therefore, to bypass this first-pass metabolism, olanzapine could be administered via other routes rather than the oral one e.g. rectal, injections, transdermal, etc
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.08.Ph.D.2012.Ne.F (Browse shelf(Opens below)) Not for loan 01010110059561000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.08.Ph.D.2012.Ne.F (Browse shelf(Opens below)) 59561.CD Not for loan 01020110059561000

Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics

Olanzapine is an effective antipsychotic drug used for the treatment of positive and negative symptoms of schizophrenia. But, it suffers from extensive first-pass metabolism in the liver to inactive metabolites, resulting in a poor oral bioavailability of nearly 60%. Therefore, to bypass this first-pass metabolism, olanzapine could be administered via other routes rather than the oral one e.g. rectal, injections, transdermal, etc

Issued also as CD

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