Novel delivery of oseltamivir phosphate dry powder inhalation-formulation and in-vitro characterization / Shahir Ashraf Wagdy Aziz ; Supervised Hanan M. Ellaithy
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قاعة الثقاقات الاجنبية - الدور الثالث | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.34.M.Sc.2011.Sh.N (Browse shelf(Opens below)) | Not for loan | 01010110060250000 |
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Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmacology and Toxicology
Oseltamivir phosphate (OP) is an antiviral drug available only as oral therapy for the treatment of Influenza . The aim of this work is to formulate OP as a dry powder inhalation (DPI) using a novel developed inhaler device (UNI-Haler) for faster targeting and more efficient therapy . Micronized (0.5-5om) and milled (17-45om) Lactose , Trehalose , Mannito and Glucose were used as inert carriers for the preparation of OP DPI formulations
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