Structure-based design and synthesis of novel Ý-carboline derivatives and their biological evaluation as phosphodiesterase 5 inhibitors and anticancer agents / Amal Hassan Ali Hassan ; Supervised Ashraf H. Abadi , Nermin Salah Ahmed

By:

Amal Hassan Ali Hassan

Contributor(s):

Material type: Text

TextLanguage: English Publication details: Cairo : Amal Hassan Ali Hassan , 2011Description: 98 Leaves : facsimiles ; 30cmOther title:

التصميم القائم على الهيكل و تشييد مشتقات جديدة من البيتا كاربولين و تقييمهم الأحياني كمثبطات لإنزيم فوسفوداي إستريز ٥ و كعوامل مضادة للسرطان [Added title page title]

Online resources:

Click here to access online

Dissertation note: Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry Summary: Tadalafil, a Ý-carboline derivatives that has been introduced to the market for treatment of Male Erectile Dysfunction, acts through inhibition of Phosphodiesterase 5, leading to elevation of cGMP, vascular relaxation in the corpora cavernosa and penile erection during sexual stimulation. The safety, tolerability of PDE5 inhibition as well as the involvement of cGMP as a key component in itracellular signaling may provide new therapeutic applications for this class of drugs

Tags from this library: No tags from this library for this title. Log in to add tags.

Average rating: 0.0 (0 votes)

Holdings
Item type	Current library	Home library	Call number	Status	Barcode
Thesis	قاعة الثقاقات الاجنبية - الدور الثالث	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.34.M.Sc.2011.Am.S (Browse shelf(Opens below))	Not for loan	01010110060172000

Browsing المكتبة المركزبة الجديدة - جامعة القاهرة shelves Close shelf browser (Hides shelf browser)

Previous	No cover image available	No cover image available	No cover image available	No cover image available	No cover image available	No cover image available	No cover image available	Next
Previous	Cai01.34.M.Sc.2011.Ah.O OFDMA scheduling algorithms in WiMAX for rTPS QoS class /	Cai01.34.M.Sc.2011.Am.C A cluster and graph routing approach in multi - agent planning /	Cai01.34.M.Sc.2011.Am.E The effect of amphotericin-B on the biofilms of candida species using in vitro pharmacokinetics models /	Cai01.34.M.Sc.2011.Am.S Structure-based design and synthesis of novel Ý-carboline derivatives and their biological evaluation as phosphodiesterase 5 inhibitors and anticancer agents /	Cai01.34.M.Sc.2011.An.F Four-level unequal error protection over a scalable video coding based on H.264/AVC /	Cai01.34.M.Sc.2011.Fa.A Antimicrobial activity of metallic silver nanoparticles in combination with photothermal blue light and selected antibiotics against resistant isolates of staphylococcus aureus /	Cai01.34.M.Sc.2011.Fa.W Web - based VRML to WebGL converter application /	Next

Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry

Tadalafil, a Ý-carboline derivatives that has been introduced to the market for treatment of Male Erectile Dysfunction, acts through inhibition of Phosphodiesterase 5, leading to elevation of cGMP, vascular relaxation in the corpora cavernosa and penile erection during sexual stimulation. The safety, tolerability of PDE5 inhibition as well as the involvement of cGMP as a key component in itracellular signaling may provide new therapeutic applications for this class of drugs

There are no comments on this title.

to post a comment.

Click on an image to view it in the image viewer