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Transferosomes as delivery system for topical photodynamic therapy / Doaa Ahmed Abdelfadeel ; Supervised Kawser Nazmi Kassab , Maha Fadel Mohammed

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Doaa Ahmed Abdelfadeel , 2013Description: 104 P. : photographs ; 25cmOther title:
  • الترانسفيروزومات كموصلات فى العلاج الضوئى الديناميكى [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (Ph.D.) - Cairo University - National Institute of Laser Enhanced Science - Department of Laser Application in Medical Summary: The efficacy of transfersomes (flexible liposomes) as a novel technique for topical delivery of the hydrophilic tetra-anionic photodynamic sensitizer aluminum ({u2162}) phthalocyanine tetrasulfonate (AIPcS4) was investigated, on mammalian fibroblasts and on Balb/c mice dorsal skin. AIPcS4 was loaded in transfersomes composed of phosphatidylcholine from soy bean and sodium deoxycholate as edge activator (5:1, 10:1, and 15:1 w/w, ratios), resulting in 110-, 160-, and 200-nm mean size vesicles with encapsulation efficiencies of 16, 25, and 30%, respectively
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.24.03.Ph.D.2013.Do.T (Browse shelf(Opens below)) Not for loan 01010110062218000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.24.03.Ph.D.2013.Do.T (Browse shelf(Opens below)) 62218.CD Not for loan 01020110062218000

Thesis (Ph.D.) - Cairo University - National Institute of Laser Enhanced Science - Department of Laser Application in Medical

The efficacy of transfersomes (flexible liposomes) as a novel technique for topical delivery of the hydrophilic tetra-anionic photodynamic sensitizer aluminum ({u2162}) phthalocyanine tetrasulfonate (AIPcS4) was investigated, on mammalian fibroblasts and on Balb/c mice dorsal skin. AIPcS4 was loaded in transfersomes composed of phosphatidylcholine from soy bean and sodium deoxycholate as edge activator (5:1, 10:1, and 15:1 w/w, ratios), resulting in 110-, 160-, and 200-nm mean size vesicles with encapsulation efficiencies of 16, 25, and 30%, respectively

Issued also as CD

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