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Influence of vitamin D receptor gene polymorphisms on treatment of chronic HCV patients with interferon / Shymaa Elsayed Ayoub ; Supervised Olfat Gamil Shaker , Yassser Hussein Nassar , Maisa Said Elrazki

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Shymaa Elsayed Ayoub , 2014Description: 99 P. : facsimiles ; 25cmOther title:
  • تعدد الاشكال من الجينات لمستقبلات فيتامين د و مدى مستوياته فى الدم فى مرضى الالتهاب الكبدى الوبائى سى المعالجين بالانترفيرون [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry Summary: Chronic infection with hepatitis C virus (HCV) is a huge problem both globally and at the level of the individual patient. The natural outcome and response to treatment in hepatitis C virus (HCV) infection varies between individuals. Our aim is to detect the Influence of Vitamin D receptor gene polymorphisms (BsmI) and (Fok1) and Vit. D level in the blood of chronic liver disease patients under treatment with interferon. Blood samples were taken from 103 patients who are suffering from chronic hepatitis C disease. They were divided into Respoders (n = 63)and Non- Responders (n = 40)according to their initial response to treatment with normalization of aminotransferases (ALT and AST) levels and clearance of the virus denoted by negative HCV - RNA by PCR after 6 months of receiving treatment
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.03.Ph.D.2014.Sh.I (Browse shelf(Opens below)) Not for loan 01010110064373000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.03.Ph.D.2014.Sh.I (Browse shelf(Opens below)) 64373.CD Not for loan 01020110064373000

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry

Chronic infection with hepatitis C virus (HCV) is a huge problem both globally and at the level of the individual patient. The natural outcome and response to treatment in hepatitis C virus (HCV) infection varies between individuals. Our aim is to detect the Influence of Vitamin D receptor gene polymorphisms (BsmI) and (Fok1) and Vit. D level in the blood of chronic liver disease patients under treatment with interferon. Blood samples were taken from 103 patients who are suffering from chronic hepatitis C disease. They were divided into Respoders (n = 63)and Non- Responders (n = 40)according to their initial response to treatment with normalization of aminotransferases (ALT and AST) levels and clearance of the virus denoted by negative HCV - RNA by PCR after 6 months of receiving treatment

Issued also as CD

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