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Steady - state serum levels of vascular cell adhesion molecule -1 in children with sickle cell disease : Relevance to stroke risk and disease severity / Ahmed Ibrahim Amin Ibrahim ; Supervised Mona Hassan Eltagui , Mona Kamal Elghamrawy , Foad Abdelmonem Abdallah

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Ahmed Ibrahim Amin Ibrahim , 2014Description: 154 P. : charts , facsimiles ; 25cmOther title:
  • مستوى الجزىء الخلوى الالتصاقى رقم 1 فى الدم و علاقته بحدوث الجلطات المخية و شدة المرض فى الاطفال المرضى بأنيميا الخلايا المنجلية [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics Summary: Our study conducted on 85 patients with SCD aged 2 - 18 years, 8.4% of patients showed high risk study and 12.0% were conditional. One high risk patient had the qualifying velocity in ACA only. Regression analysis showed transfusion and HU dose protective against stroke. Mean VCAM level was 1438.12 ± 848.2 ng / ml and significantly higher than of normal population and higher in patient with normal TCD (P. 038). However, correlation of VCAM level with TAMMvel using showed + ve correlation with (P. 041). Levels were higher in HbSÝ subgroup, higher bilirubin level (and frequency of blood transfusion). In SS subgroup, VCAM level was significantly correlated with severity frequency (P {u2264}. 001) and duration (P {u2264}. 001) of VOCs. Level was lower with HU treatment P. 041
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Item type Current library Home library Call number Copy number Status Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.Ph.D.2014.Ah.S (Browse shelf(Opens below)) Not for loan 01010110065504000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.Ph.D.2014.Ah.S (Browse shelf(Opens below)) 65504.CD Not for loan 01020110065504000

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics

Our study conducted on 85 patients with SCD aged 2 - 18 years, 8.4% of patients showed high risk study and 12.0% were conditional. One high risk patient had the qualifying velocity in ACA only. Regression analysis showed transfusion and HU dose protective against stroke. Mean VCAM level was 1438.12 ± 848.2 ng / ml and significantly higher than of normal population and higher in patient with normal TCD (P. 038). However, correlation of VCAM level with TAMMvel using showed + ve correlation with (P. 041). Levels were higher in HbSÝ subgroup, higher bilirubin level (and frequency of blood transfusion). In SS subgroup, VCAM level was significantly correlated with severity frequency (P {u2264}. 001) and duration (P {u2264}. 001) of VOCs. Level was lower with HU treatment P. 041

Issued also as CD

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