Photostability study and formulation of indocyanine green in topical pharmaceutical formula / Sarah Salah Thabet Ali ; Supervised Kawser Nazmi Kassab , Maha Fadel Mohamed

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Sarah Salah Thabet Ali

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TextLanguage: English Publication details: Cairo : Sarah Salah Thabet Ali , 2014Description: 95 P. : charts , facsimiles ; 25cmOther title:

دراسة الثبات الضوئى للاندوسيانين الأخضر وتحضيره فى تركيبة صيدلية موضعية [Added title page title]

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Dissertation note: Thesis (M.Sc.) - Cairo University - National Institute of Laser Enhanced Sciences - Department of Laser Applications Medical and Biological Summary: This study aimed to develop transfersomes entrapping Indocyanine green (ICG) and formulation in hydrogel form to enhance ICG dark- and- photostability as well as improving its topical delivery as photodynamic sensitizer. Four transfersomal preparations entrapping ICG either in the lipid membrane or the aqueous core (in absence or presence of cholesterol) were formulated. All Formulations were studied for some pharmaceutical properties and for ICG dark- and- photostability. Furthermore, the best transfersomal ICG was formulated in topical hydrogel and studied for in vivo topical photodynamic therapy (PDT) on animal skin and evaluated clinically for PDT of acne vulgaris

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Item type	Current library	Home library	Call number	Copy number	Status	Barcode
Thesis	قاعة الرسائل الجامعية - الدور الاول	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.24.05.M.Sc.2014.Sa.P (Browse shelf(Opens below))		Not for loan	01010110065626000
CD - Rom	مخـــزن الرســائل الجـــامعية - البدروم	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.24.05.M.Sc.2014.Sa.P (Browse shelf(Opens below))	65626.CD	Not for loan	01020110065626000

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Thesis (M.Sc.) - Cairo University - National Institute of Laser Enhanced Sciences - Department of Laser Applications Medical and Biological

This study aimed to develop transfersomes entrapping Indocyanine green (ICG) and formulation in hydrogel form to enhance ICG dark- and- photostability as well as improving its topical delivery as photodynamic sensitizer. Four transfersomal preparations entrapping ICG either in the lipid membrane or the aqueous core (in absence or presence of cholesterol) were formulated. All Formulations were studied for some pharmaceutical properties and for ICG dark- and- photostability. Furthermore, the best transfersomal ICG was formulated in topical hydrogel and studied for in vivo topical photodynamic therapy (PDT) on animal skin and evaluated clinically for PDT of acne vulgaris

Issued also as CD

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