header
Local cover image
Local cover image
Image from OpenLibrary

Study the effect of nano and micro encapsulation of DNA vaccine model on its stability and immunogenicity / Heba Ibrahim Mohamed Abdallah ; Supervised Mahmoud Mohamed Ghorab , Aly Fahmy Mohamed

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Heba Ibrahim Mohamed Abdallah , 2017Description: 172 P. : charts , facsimiles ; 25cmOther title:
  • دراسة تأثير الصياغة على الثبات والقدرة المناعية لنموذج لقاح حامض الديكسيريبوز فى صورة حويصلات دقيقة او نانو مترية [Added title page title]
Subject(s): Online resources: Available additional physical forms:
  • Issued also as CD
Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics Summary: Herpes simplex virus type 2 (HSV-2) is a one of the most prevalent worldwide sexually transmitted infection. HSV-2 causes recurrent genital ulcers, neonatal herpes, and also, increases the risk for human immunodeficiency virus (HIV) acquisition. Many HSV-2 vaccines have been tested in humans, but were not consistently effective. In the present work we tried to produce a model vaccine for HSV-2 formulated in different formulae as an attempt for development of an effective prophylactic and therapeutic HSV-2 vaccine. Beta propiolactone (BPL) as a virus inactivant was compared with the conventional formalin (F). Gold and silver nanoparticles were prepared with different concentrations as a vaccine adjuvants. Also, calcium phosphate nanoparticles and bovine serum albumin nanoparticles were used as vaccine adjuvants . They were compared with currently used aluminum phosphate gel (alum) microparticles
Tags from this library: No tags from this library for this title. Log in to add tags.
Star ratings
    Average rating: 0.0 (0 votes)
Holdings
Item type Current library Home library Call number Copy number Status Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.08.Ph.D.2017.He.S (Browse shelf(Opens below)) Not for loan 01010110073737000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.08.Ph.D.2017.He.S (Browse shelf(Opens below)) 73737.CD Not for loan 01020110073737000

Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics

Herpes simplex virus type 2 (HSV-2) is a one of the most prevalent worldwide sexually transmitted infection. HSV-2 causes recurrent genital ulcers, neonatal herpes, and also, increases the risk for human immunodeficiency virus (HIV) acquisition. Many HSV-2 vaccines have been tested in humans, but were not consistently effective. In the present work we tried to produce a model vaccine for HSV-2 formulated in different formulae as an attempt for development of an effective prophylactic and therapeutic HSV-2 vaccine. Beta propiolactone (BPL) as a virus inactivant was compared with the conventional formalin (F). Gold and silver nanoparticles were prepared with different concentrations as a vaccine adjuvants. Also, calcium phosphate nanoparticles and bovine serum albumin nanoparticles were used as vaccine adjuvants . They were compared with currently used aluminum phosphate gel (alum) microparticles

Issued also as CD

There are no comments on this title.

to post a comment.

Click on an image to view it in the image viewer

Local cover image