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Novel strychnine dimers as bivalent ligands targeting glycine receptors / Liza Samir Samy Botros ; Supervised Darius P. Zlotos

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Liza Samir Samy Botros , 2017Description: 128 Leaves : charts ; 30cmOther title:
  • متشابهات ستركنين ثنائية التركيب جديدة كمثبطات لمستقبلات الجلايسين [Added title page title]
Online resources: Dissertation note: Thesis (M.Sc.) - German University - Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry Summary: Strychnine in the major alkaloid from the seeds of Strychnos nux-vomica and strychnos ignati. As a natural product, its structure has been optimized for strong interactions with biological macromolecules through evolutionary selection. Its most pronounced pharmacological action is an antagonistic activity at glycine receptors (GlyRs)
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Thesis (M.Sc.) - German University - Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry

Strychnine in the major alkaloid from the seeds of Strychnos nux-vomica and strychnos ignati. As a natural product, its structure has been optimized for strong interactions with biological macromolecules through evolutionary selection. Its most pronounced pharmacological action is an antagonistic activity at glycine receptors (GlyRs)

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