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Vitamin D status in acute ischemic stroke / Sarah Sherif Mahmoud Abdo ; Supervised Ebtesam Mohamed Fahmy , Hanan Helmy Mohamed , Sahar Abdelatty

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Sarah Sherif Mahmoud Abdo , 2018Description: 115 P. : charts ; 25cmOther title:
  • حالة فيتامين (د) فى سكتة قصور التروية الدماغية الحادة [Added title page title]
Subject(s): Available additional physical forms:
  • Issued also as CD
Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Neuropsychiatry Summary: Background: A growing body of evidence indicated that vitamin D has a potential protective role against neurovascular injury. Specifically, low serum 25(OH) Vitamin D has been associated with increased risk for incident stroke and stroke fatality. Exact causality is however not yet established. Objectives: This study aimed to explore vitamin D status among acute ischemic stroke patients and its relation to initial severity and short-term outcome of acute ischemic stroke. Subjects and methods: The study was carried on forty-eight acute ischemic stroke patients and forty-eight matched healthy control subjects. Serum vitamin D was done for all patients and control subjects. National Institute of Health Stroke Scale (NIHSS) on admission and after 72 hours and modified Rankin Scale (mRS) on discharge and after 3 months were performed for all patients. Measurement of serum vitamin D was done for all patients and control subjects. Serum C Reactive Protein (CRP) and calcium were also done for all patients. Brain computed Tomography (CT) scan was also done for all patients and the volume of infarction was obtained. Carotid and vertebrobasilar duplex was done for thirty patients. Results: There was a statistically highly significant difference between patients and controls regarding serum vitamin D levels being lower in the patients group. Vitamin D deficiency and insufficiency were also significantly prevalent among stroke patients compared to healthy controls. A statistically significant difference was detected between patients{u2019} subgroups distributed according to vitamin D status regarding mean age. Hypertension was more prevalent in the deficient subgroup. Patients with deficient vitamin D had more severe stroke and worse short term outcome compared to other subgroups
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.21.M.Sc.2018.Sa.V (Browse shelf(Opens below)) Not for loan 01010110076325000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.21.M.Sc.2018.Sa.V (Browse shelf(Opens below)) 76325.CD Not for loan 01020110076325000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Neuropsychiatry

Background: A growing body of evidence indicated that vitamin D has a potential protective role against neurovascular injury. Specifically, low serum 25(OH) Vitamin D has been associated with increased risk for incident stroke and stroke fatality. Exact causality is however not yet established. Objectives: This study aimed to explore vitamin D status among acute ischemic stroke patients and its relation to initial severity and short-term outcome of acute ischemic stroke. Subjects and methods: The study was carried on forty-eight acute ischemic stroke patients and forty-eight matched healthy control subjects. Serum vitamin D was done for all patients and control subjects. National Institute of Health Stroke Scale (NIHSS) on admission and after 72 hours and modified Rankin Scale (mRS) on discharge and after 3 months were performed for all patients. Measurement of serum vitamin D was done for all patients and control subjects. Serum C Reactive Protein (CRP) and calcium were also done for all patients. Brain computed Tomography (CT) scan was also done for all patients and the volume of infarction was obtained. Carotid and vertebrobasilar duplex was done for thirty patients. Results: There was a statistically highly significant difference between patients and controls regarding serum vitamin D levels being lower in the patients group. Vitamin D deficiency and insufficiency were also significantly prevalent among stroke patients compared to healthy controls. A statistically significant difference was detected between patients{u2019} subgroups distributed according to vitamin D status regarding mean age. Hypertension was more prevalent in the deficient subgroup. Patients with deficient vitamin D had more severe stroke and worse short term outcome compared to other subgroups

Issued also as CD

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