header
Image from OpenLibrary

Detection of carbapenemase producing Enterobacteriaceae using the modified carbapenem inactivation method / Hagar Lotfy Abdelbaky Mowafy ; Supervised Mohammad Amr Elkholy , Maha Mahmoud Kotb

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Hagar Lotfy Abdelbaky Mowafy , 2018Description: 88 P. : charts , facsimiles ; 25cmOther title:
  • الكشف عن البكتريا المعوية المنتجة للكاربابنيميز باستخدام طريقة تعطيل الكاربابينيم المعدلة [Added title page title]
Subject(s): Available additional physical forms:
  • Issued also as CD
Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Microbiology and Immunology Summary: Carbapenems are a class of beta (Ý)-lactam antibiotics with broad spectrum of activity. They are often considered as a last resort in treatment of infections caused by multidrug resistant organisms. Carbapenem resistant Enterobacteriaceae (CRE) have been reported worldwide. Resistance to carbapenems in Enterobacteriaceae is caused mainly by carbapenemase production or by porin loss combined with the expression of Ý-lactamases like extended-spectrum Ý-lactamases (ESBL) or ampicillin class C (AmpC). In the present study, we attempted to determine the prevalence of carbapenemase-producing Enterobacteriaceae (CPE) among 202 clinical isolates of Enterobacteriaceae by the phenotypic test modified carbapenem inactivation method (mCIM) Initial screening for carbapenemase- producing isolates among the 202 Enterobacteriaceae isolates was done by minimum inhibitory concentration (MIC) determination for ertapenem by broth microdilution method. Confirmation of carbapenemase production among ertapenem-resistant isolates was done by the phenotypic test mCIM. The results of the current study showed that the prevalence of CRE by broth microdilution method was 36.1% and the prevalence of CPE among resistant isolates was 80.8% by mCIM
Tags from this library: No tags from this library for this title. Log in to add tags.
Star ratings
    Average rating: 0.0 (0 votes)
Holdings
Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.19.M.Sc.2018.Ha.D (Browse shelf(Opens below)) Not for loan 01010110077332000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.19.M.Sc.2018.Ha.D (Browse shelf(Opens below)) 77332.CD Not for loan 01020110077332000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Microbiology and Immunology

Carbapenems are a class of beta (Ý)-lactam antibiotics with broad spectrum of activity. They are often considered as a last resort in treatment of infections caused by multidrug resistant organisms. Carbapenem resistant Enterobacteriaceae (CRE) have been reported worldwide. Resistance to carbapenems in Enterobacteriaceae is caused mainly by carbapenemase production or by porin loss combined with the expression of Ý-lactamases like extended-spectrum Ý-lactamases (ESBL) or ampicillin class C (AmpC). In the present study, we attempted to determine the prevalence of carbapenemase-producing Enterobacteriaceae (CPE) among 202 clinical isolates of Enterobacteriaceae by the phenotypic test modified carbapenem inactivation method (mCIM) Initial screening for carbapenemase- producing isolates among the 202 Enterobacteriaceae isolates was done by minimum inhibitory concentration (MIC) determination for ertapenem by broth microdilution method. Confirmation of carbapenemase production among ertapenem-resistant isolates was done by the phenotypic test mCIM. The results of the current study showed that the prevalence of CRE by broth microdilution method was 36.1% and the prevalence of CPE among resistant isolates was 80.8% by mCIM

Issued also as CD

There are no comments on this title.

to post a comment.