Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics

Renal biopsy became a standard technique in diagnosing renal diseases. It held many complications in the past being performed blindly. But since the introduction of ultrasound guided renal biopsy in the field, the procedure became much safer with less complication rate and better yield. Objectives: In this study we aim to evaluate the capability of ultrasound examination after one hour to detect early complication and predict the course of cases. Patients and methods: This was a prospective study conducted during the period from October 2017 to the end of March 2018, and included patients undergoing Percutaneous Renal Biopsy in the Pediatric Nephrology Unit in Cairo University Pediatric Hospitals. Results: The present study was conducted on 60 patients; 29 were males (48.3%) and 31 were females (51.7%); their mean weight was 24.2 kg, with mean age 89.3 months. Out of 60 patients who performed the biopsy, only 21.6% had complications. We detected two subcapsular hematomas (3.3%), another 2 cases with bladder hematoma (3.3%), 9 cases with back pain (15%) and hematuria (as a complication, not related to original disease) occurred in 6 cases (10%). We found that sensitivity of ultrasound is 66.6% in the first hour after renal biopsy with 98.3 % specificity to possible bleeding complications with 66.6% positive predictive value and 98.2% negative predictive value. However clinical presentation was the only predictor in one case for complication which was detected late by ultrasound

Issued also as CD