Preparation and characterization of modified Ion selective electrodes and their application In determination of some drugs / Mohamed Hamdy Abo Elhamd Ahmed ; Supervised Mohamed Mohamed Ahmed Omar , Tamer Awad Ali

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Mohamed Hamdy Abo Elhamd Ahmed

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TextLanguage: English Publication details: Cairo : Mohamed Hamdy Abo Elhamd Ahmed , 2018Description: 112 P. : charts ; 25cmOther title:

تحضير و توصيف أقطاب أيونية أنتقائية معدلة و تطبيقاتها فى تقدير بعض الأدوية [Added title page title]

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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Analytical Chemistry Summary: The construction and performance characteristics of new modified screen printed (MSPE) and carbon paste (MCPE) electrodes for determination of metoclopramide hydrochloride (MCPHC) drug based on the ion-pair formation between MCP with sodium tetraphenylborate (Na-TPB) in pure, pharmaceutical preparations and biological fluids have been investigated. Different experimental conditions namely types of materials used to fabricate the working electrode (plasticizer), titrant, pH, temperature and life time were studied. The fabricated electrodes demonstrated near Nernstian response over wide linear range of 1.0{u00D7}10{u2013}6-1.0{u00D7}10-2 mol L-1 metoclopramide with lower limit of detection of 1.0{u00D7}10-6 mol L-1 and slopes of 58.10±0.31 mV decade-1 and 58.90±0.15 mV decade-1 over pH range 3.0-8.0 and 3.0{u2013}7.0 for MCPE and MSPE, respectively. The MSPE and MCPE denoted a fast response time of 3 and 2 s and can be utilized at least 83 and 175 days without any remarkable deviations for MCPE and MSPE, respectively. The proposed electrodes displayed good selectivity for MCPHC with respect to number of potential interfering substances as inorganic cations, sugars and other pharmaceutical excipients

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Holdings
Item type	Current library	Home library	Call number	Copy number	Status	Date due	Barcode
Thesis	قاعة الرسائل الجامعية - الدور الاول	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.12.08.M.Sc.2018.Mo.P (Browse shelf(Opens below))		Not for loan		01010110078966000
CD - Rom	مخـــزن الرســائل الجـــامعية - البدروم	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.12.08.M.Sc.2018.Mo.P (Browse shelf(Opens below))	78966.CD	Not for loan		01020110078966000

Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Analytical Chemistry

The construction and performance characteristics of new modified screen printed (MSPE) and carbon paste (MCPE) electrodes for determination of metoclopramide hydrochloride (MCPHC) drug based on the ion-pair formation between MCP with sodium tetraphenylborate (Na-TPB) in pure, pharmaceutical preparations and biological fluids have been investigated. Different experimental conditions namely types of materials used to fabricate the working electrode (plasticizer), titrant, pH, temperature and life time were studied. The fabricated electrodes demonstrated near Nernstian response over wide linear range of 1.0{u00D7}10{u2013}6-1.0{u00D7}10-2 mol L-1 metoclopramide with lower limit of detection of 1.0{u00D7}10-6 mol L-1 and slopes of 58.10±0.31 mV decade-1 and 58.90±0.15 mV decade-1 over pH range 3.0-8.0 and 3.0{u2013}7.0 for MCPE and MSPE, respectively. The MSPE and MCPE denoted a fast response time of 3 and 2 s and can be utilized at least 83 and 175 days without any remarkable deviations for MCPE and MSPE, respectively. The proposed electrodes displayed good selectivity for MCPHC with respect to number of potential interfering substances as inorganic cations, sugars and other pharmaceutical excipients

Issued also as CD

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