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Study effects of adding cabergoline by different doses to coasting reduce the incidence ovarian hyperstimulation syndrome : A randomized controlled study / Ahmed Othman Ahmed Sayed Ahmed ; Supervised Tarek Fawzy , Ahmed Maged , Abdelghany Mohamed

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Ahmed Othman Ahmed Sayed Ahmed , 2020Description: 126 P. : charts ; 25cmOther title:
  • دراسة آثار إضافة كابر جولين بجرعات مختلفة إلى إيقاف المنشط فى تحفيظ نسبة متلازمة فرط الأستجابة للمبيض : دراسة عشوائية منضبطة [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Gynecology and Obstetrics Summary: Background:Ovarian hyperstimulation syndrome (OHSS) is a potentially severe iatrogenic complication of controlled ovarian stimulation. Combining coasting and cabergoline may be beneficial for preventing OHSS, but this has not been well investigated. Objectives:To compare the effectiveness and safety of combined cabergoline and coasting versus coasting alone for preventing OHSS in high-risk women undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI). Methods:The present double-blinded randomized controlled trial was conducted at Al-Ahram Fertility Center (Mansoura, Egypt) between January 2016 and December 2018. 200 patients undergoing IVF/ICSI at high risk of OHSS were equally randomized to coasting or combined coasting and cabergoline. The main measured outcomes were the rate and severity of OHSS, number of retrieved oocytes, number and quality of embryos, as well as rates of fertilization, implantation,chemical, and clinical pregnancy. Results:The combination group has a lower rate of OHSS (4% vs. 18%, p 0.001) and higher number of good embryos (12.1 ±3.93 vs. 6.9 ±2.67; p< 0.00). There were no significant differences between the two groups in the number of retrieved oocytes as well as the rates of fertilization, implantation,chemical, and clinical pregnancy
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.15.Ph.D.2020.Ah.S (Browse shelf(Opens below)) Not for loan 01010110083126000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.15.Ph.D.2020.Ah.S (Browse shelf(Opens below)) 83126.CD Not for loan 01020110083126000
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Cai01.11.15.Ph.D.2020.Ah.E Extended letrozole regimen co-treatment with gonadotropin releasing hormone antagonist protocol versus gonadotropin releasing hormone antagonist protocol in poor responders undergoing IVF-ET : A randomized controlled trial / Cai01.11.15.Ph.D.2020.Ah.F Fetal central nervous system anomalies : Evaluating the role of 2D and 3D ultrasound, abdominal versus vaginal fetal neurosonogram in second and third trimesters of pregnancy / Cai01.11.15.Ph.D.2020.Ah.F Fetal central nervous system anomalies : Evaluating the role of 2D and 3D ultrasound, abdominal versus vaginal fetal neurosonogram in second and third trimesters of pregnancy / Cai01.11.15.Ph.D.2020.Ah.S Study effects of adding cabergoline by different doses to coasting reduce the incidence ovarian hyperstimulation syndrome : A randomized controlled study / Cai01.11.15.Ph.D.2020.Ah.S Study effects of adding cabergoline by different doses to coasting reduce the incidence ovarian hyperstimulation syndrome : A randomized controlled study / Cai01.11.15.Ph.D.2020.Am.T Two{u2013}dimentional (2D) ultrasound for the prediction of fetal hypertrophic cardiomyopathy and comparing it with postnatal echocardiography among diabetic pregnant women / Cai01.11.15.Ph.D.2020.Am.T Two{u2013}dimentional (2D) ultrasound for the prediction of fetal hypertrophic cardiomyopathy and comparing it with postnatal echocardiography among diabetic pregnant women /

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Gynecology and Obstetrics

Background:Ovarian hyperstimulation syndrome (OHSS) is a potentially severe iatrogenic complication of controlled ovarian stimulation. Combining coasting and cabergoline may be beneficial for preventing OHSS, but this has not been well investigated. Objectives:To compare the effectiveness and safety of combined cabergoline and coasting versus coasting alone for preventing OHSS in high-risk women undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI). Methods:The present double-blinded randomized controlled trial was conducted at Al-Ahram Fertility Center (Mansoura, Egypt) between January 2016 and December 2018. 200 patients undergoing IVF/ICSI at high risk of OHSS were equally randomized to coasting or combined coasting and cabergoline. The main measured outcomes were the rate and severity of OHSS, number of retrieved oocytes, number and quality of embryos, as well as rates of fertilization, implantation,chemical, and clinical pregnancy. Results:The combination group has a lower rate of OHSS (4% vs. 18%, p 0.001) and higher number of good embryos (12.1 ±3.93 vs. 6.9 ±2.67; p< 0.00). There were no significant differences between the two groups in the number of retrieved oocytes as well as the rates of fertilization, implantation,chemical, and clinical pregnancy

Issued also as CD

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