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Improvement availability of drug for certain eye delivery systems / Sammar Fathy Elhabal ; Supervised Mohamed Ahmed Elnbarawi , Nevine Shawky AbdelMalak , Rehab Ahmed Abdelmonem

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Sammar Fathy Elhabal , 2021Description: 140 P. : charts , facimiles ; 25cmOther title:
  • تحسين الإتاحة لعقار فى بعض أنظمة العلاج عن طريق العين [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics Summary: This study was performed to investigate the topical effectiveness of acetazolamide, carvedilol and combination of them for glaucoma treatment as recently investigated. The aim of the study was to prepare combination of acetazolamide and carvedilol loaded niosomes as ocular drug delivery system to decrease side effect of both drugs when taken by oral route like water retention of Ý-blocker side effect .Sustained effect of gel noisomal gel combination as ocular drug delivery system all increase bioavailability and patient-compliance form eye drops, and gel, ensuring the appropriate release kinetics.Ex-vivo and in-vivo permeability and bioavailability were assessed in comparison with a solution of them and niosomes of each other alone
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Item type Current library Home library Call number Copy number Status Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.08.Ph.D.2021.Sa.I (Browse shelf(Opens below)) Not for loan 01010110083599000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.08.Ph.D.2021.Sa.I (Browse shelf(Opens below)) 83599.CD Not for loan 01020110083599000

Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics

This study was performed to investigate the topical effectiveness of acetazolamide, carvedilol and combination of them for glaucoma treatment as recently investigated. The aim of the study was to prepare combination of acetazolamide and carvedilol loaded niosomes as ocular drug delivery system to decrease side effect of both drugs when taken by oral route like water retention of Ý-blocker side effect .Sustained effect of gel noisomal gel combination as ocular drug delivery system all increase bioavailability and patient-compliance form eye drops, and gel, ensuring the appropriate release kinetics.Ex-vivo and in-vivo permeability and bioavailability were assessed in comparison with a solution of them and niosomes of each other alone

Issued also as CD

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