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Cardiac affections associated with hyper immunoglobulin E syndrome / Dina Ibrahim Elbasuony ; Supervised Soha Mohamed Emam , Dalia Salaheldin Ahmed , Mohamed Ali Sami

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Dina Ibrahim Elbasuony , 2021Description: 110 P . : charts , facsimiles ; 25cmOther title:
  • Eمشاكل الشرايين التاجية المصاحبة لمتلازمة الفرط المناعى [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics Summary: Background: Hyper-Immunoglobulin E syndrome (HIES) is a primary immune deficiency disorder, which is characterized by eczema, recurrent infections and elevated serum IgE. Several case reports described coronary abnormalities in STAT3-HIES. Aim of the study: this study was conducted to detect coronary abnormalities associated with DOCK8 defect-HIES patients. Methods: This cross-sectional study included fifteen pediatric patients diagnosed with DOCK8 defect-HIES, who were followed up at the Immunology Outpatient Clinic, Cairo University Children{u2019}s Hospitals. All patients were subjected to thorough history taking, clinical examination, and immunological profile. Also, cardiac troponin I level, 12-lead electrocardiography, echocardiography, and multislice computed tomography (MSCT) angiography, were performed. Data were collected and subjected for statistical analysis Results: The mean age was 6.80±4.55 years and the male: female ratio was 2:1. Statistical analysis showed that 10 (66%) patients had low CD4%, 8 (53%) patients had low CD3% and 3 (20%) patients had low CD8%. Four (26%) patients had elevated troponin I levels. All echocardiographic parameters (M and 2D modes as well as tissue Doppler) were normal. Both echocardiography and MSCT angiography revealed normal sizes of the right coronary, left coronary, left anterior descending, and circumflex coronary arteries
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.M.Sc.2021.Di.C (Browse shelf(Opens below)) Not for loan 01010110083749000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.M.Sc.2021.Di.C (Browse shelf(Opens below)) 83749.CD Not for loan 01020110083749000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics

Background: Hyper-Immunoglobulin E syndrome (HIES) is a primary immune deficiency disorder, which is characterized by eczema, recurrent infections and elevated serum IgE. Several case reports described coronary abnormalities in STAT3-HIES. Aim of the study: this study was conducted to detect coronary abnormalities associated with DOCK8 defect-HIES patients. Methods: This cross-sectional study included fifteen pediatric patients diagnosed with DOCK8 defect-HIES, who were followed up at the Immunology Outpatient Clinic, Cairo University Children{u2019}s Hospitals. All patients were subjected to thorough history taking, clinical examination, and immunological profile. Also, cardiac troponin I level, 12-lead electrocardiography, echocardiography, and multislice computed tomography (MSCT) angiography, were performed. Data were collected and subjected for statistical analysis Results: The mean age was 6.80±4.55 years and the male: female ratio was 2:1. Statistical analysis showed that 10 (66%) patients had low CD4%, 8 (53%) patients had low CD3% and 3 (20%) patients had low CD8%. Four (26%) patients had elevated troponin I levels. All echocardiographic parameters (M and 2D modes as well as tissue Doppler) were normal. Both echocardiography and MSCT angiography revealed normal sizes of the right coronary, left coronary, left anterior descending, and circumflex coronary arteries

Issued also as CD

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