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Phytochemicaland bioactivity evaluation of pulicaria crispa (Forssk.)oliv.and pulicariaincisa (Lam.) DC. family asteraceae growingin Egypt / Osama Ahmed Elsabagh ; Supervised Mohamed Ali Farag , Engy Abdelhamid Mahrous , Sayed Abdelhamid Eltoumy

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Osama Ahmed Elsabagh , 2021Description: 225 P. : charts , facsimiles ; 25cmOther title:
  • دراسة فيتوكيميائية وتقييم النشاط الحيوى لنباتى بوليكاريا كريسبا (فورسيك) و بوليكاريا إنسيزا(الآم) المنتميان للعائلة المركبة الناميان فى مصر [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - Facultyof Pharmacy - Department of Pharmacognosy Summary: Pulicariacrispa and Pulicariaincisa were studied herein to investigate their chemical composition using different chromatographic techniques and to assess their antioxidant, antihepatotoxic, and antimicrobial effects.The study contained the following main parts:Part-I: Phytochemical study Chapter-I: UPLC-MS profiling of secondary metabolites The aim of this work was to define and compare the phytochemical composition of Pulicariacrispaand Pulicariaincisaby using UPLC-PDA-ESI-qTOF-MSn. Extracts were analyzed in negative electrospray ion. Metabolites were eluted in order of decreasing polarity, and identification of metabolites was made by retention time, UV/Vis spectra and MS fragmentation pattern (accurate mass, isotopic distribution and fragmentation pattern in negative ion mode). Metabolites identified using UPLC-MS were analyzed by XCMS data analysis software.122metabolites belonging to various chemical classes weretentatively identified including{uFB02}avonoids (37), phenolic acids (22),sesquiterpenes (17), diterpenes (7), and fattyacids (27), with enrichment in methoxylated flavonoids (20), caffeoylquinic acid conjugates (14) xanthanesesquiterpenes (9) and hydroxylated fatty acids (20) in both Pulicaria species
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.07.Ph.D.2021.Os.P (Browse shelf(Opens below)) Not for loan 01010110084029000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.07.Ph.D.2021.Os.P (Browse shelf(Opens below)) 84029.CD Not for loan 01020110084029000

Thesis (Ph.D.) - Cairo University - Facultyof Pharmacy - Department of Pharmacognosy

Pulicariacrispa and Pulicariaincisa were studied herein to investigate their chemical composition using different chromatographic techniques and to assess their antioxidant, antihepatotoxic, and antimicrobial effects.The study contained the following main parts:Part-I: Phytochemical study Chapter-I: UPLC-MS profiling of secondary metabolites The aim of this work was to define and compare the phytochemical composition of Pulicariacrispaand Pulicariaincisaby using UPLC-PDA-ESI-qTOF-MSn. Extracts were analyzed in negative electrospray ion. Metabolites were eluted in order of decreasing polarity, and identification of metabolites was made by retention time, UV/Vis spectra and MS fragmentation pattern (accurate mass, isotopic distribution and fragmentation pattern in negative ion mode). Metabolites identified using UPLC-MS were analyzed by XCMS data analysis software.122metabolites belonging to various chemical classes weretentatively identified including{uFB02}avonoids (37), phenolic acids (22),sesquiterpenes (17), diterpenes (7), and fattyacids (27), with enrichment in methoxylated flavonoids (20), caffeoylquinic acid conjugates (14) xanthanesesquiterpenes (9) and hydroxylated fatty acids (20) in both Pulicaria species

Issued also as CD

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