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Formulation and dvaluation of a low dissolution drug in soft gelatin capsules with solubilized and emulsified core adjuvants / Abdalwali Ahmad Saif Hameed ; Supervised Mohamed Sayed Ahmed ElSamaligy , Omaima Naeem El Gazayerly

By: Contributor(s): Language: Eng Publication details: Cairo : Abdalwali Ahmad Saif Hameed , 2005Description: 229p : ill ; 30cmOther title:
  • صياغة وتقييم الكبسولات الجيلاتينيه الرخوة لعقار شحيح الاذابه فى سواغ مذابه ومستحلبه [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty Of Pharmacy - Department Of Pharmaceutics Summary: Many drugs have limited bioavailability due to either the influence of the physiological factors associated with the structure and function of GI tract , or the physicochemical properties of the drug and dosage form factorsAs the drug should be soluble to be absorbed , one of the methods to increase the drug availability is to deliver it in solution dosage formMany of the old drugs and most of the outcome new molecules have limited solubilityThe need to manipulate drug's poor solubility is essential to reach the desired solution concentrationSolubilization methods are : cosolvency , micellar solubilization , complexation , pH control , hydrotropy and solid dispersion , chemical modification , crystal modification and particle size reduction
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Item type Current library Home library Call number Copy number Status Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.08.M.Sc.2005.Ab.F. (Browse shelf(Opens below)) Not for loan 01010110043424000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.08.M.Sc.2005.Ab.F. (Browse shelf(Opens below)) 43424.CD Not for loan 01020110043424000

Thesis (M.Sc.) - Cairo University - Faculty Of Pharmacy - Department Of Pharmaceutics

Many drugs have limited bioavailability due to either the influence of the physiological factors associated with the structure and function of GI tract , or the physicochemical properties of the drug and dosage form factorsAs the drug should be soluble to be absorbed , one of the methods to increase the drug availability is to deliver it in solution dosage formMany of the old drugs and most of the outcome new molecules have limited solubilityThe need to manipulate drug's poor solubility is essential to reach the desired solution concentrationSolubilization methods are : cosolvency , micellar solubilization , complexation , pH control , hydrotropy and solid dispersion , chemical modification , crystal modification and particle size reduction

Issued also as CD

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