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Isolation, purification and biological evaluation of sarcophine and one of its semisynthetic derivatives from the Red Sea soft coral Sarcophyton glaucum / Hesham Adel Saleh ; Supervised Nazih Noureldin , Hans-Georg Breitinger

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Hesham Adel Saleh , 2010Description: 98Leaves : charts ; 30cmDissertation note: Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry Summary: Sarcophine is an epoxy cembranolide isolated in good yields from the Red Sea soft coral Sarcophyton glaucum showing various biological activities ; most prominent are its anticancer effects . However since the molecule is primarily a defense toxin for its coral ; utilizing this lead compound for pharmacological use is conditioned by its toxicity profile that would hinder introducing it for clinical trials if not safe levels
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Thesis Thesis قاعة الثقاقات الاجنبية - الدور الثالث المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.34.M.Sc.2010.He.I (Browse shelf(Opens below)) Not for loan 01010110060243000

Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry

Sarcophine is an epoxy cembranolide isolated in good yields from the Red Sea soft coral Sarcophyton glaucum showing various biological activities ; most prominent are its anticancer effects . However since the molecule is primarily a defense toxin for its coral ; utilizing this lead compound for pharmacological use is conditioned by its toxicity profile that would hinder introducing it for clinical trials if not safe levels

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