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Synthesis of Novel Heterocycle derivatives as potential phosphodiesterase inhibitors and anticancer / Rowaida Adel Abdelhamid Hassan ; Supervised Ashraf H. Abadi , Mohammed Abdelhalim

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Rowaida Adel Abdelhamid Hassan , 2017Description: 102 Leaves : charts , facsimiles ; 30cmOther title:
  • تشييد مشتقات جديدة من متعددة الحلقة وتقييمها كمثبطات لإنزيمات الفوسفودايستريزو كمضات للسرطان [Added title page title]
Subject(s): Online resources: Dissertation note: Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry Summary: Cyclicn nucleotide phosphodiesterase (PDEs) are promising targets for pharmacological ontervention. The presence of multiple PDE genes, diversity of the isoforms produced from each gene, selective tissue and cellular expression of the isoforms compartmentation within cells, and an array of conformations of PDE proteins are some of the properties that challenge the development of drugs that target these enzymes
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Thesis Thesis قاعة الثقاقات الاجنبية - الدور الثالث المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.34.M.Sc.2017.Ro.S (Browse shelf(Opens below)) Not for loan 01010110075360000

Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry

Cyclicn nucleotide phosphodiesterase (PDEs) are promising targets for pharmacological ontervention. The presence of multiple PDE genes, diversity of the isoforms produced from each gene, selective tissue and cellular expression of the isoforms compartmentation within cells, and an array of conformations of PDE proteins are some of the properties that challenge the development of drugs that target these enzymes

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