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The effect of curcumin on type 17 helper T cells in collagen-induced arthritis in rats / Elshaimaa Mohsen Ibrahim Mostafa ; Supervised Somaya Eldeeb , Amany Elwakkad , Abeer Badr

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Elshaimaa Mohsen Ibrahim Mostafa , 2014Description: 224 P. : charts , facsimiles ; 25cmOther title:
  • ثأثير الكركمين على نوع الخلايا تى 71 المساعدة في التهاب المفاصل المستحث بالكولاجين في الجرذان [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Zoology Summary: Rheumatoid arthritis (RA) is one of the major human systemic autoimmune diseases, affecting approximately 1% of the world population, with unknown etiology attacking synovial joints, causing bone erosion, which leads to joint deformation, fractures and severe disability. For which there is no effective cure available. CIA was chosen as an animal model of RA as it produces many of the clinical and pathological features of human RA. Male albino rats were divided into 7 groups: N, D, A, Cb, Ca, M and CM. Treatments in groups Ca, M and CM were initiated from day 20 and continued till day 69. Blood samples were collected on days 0, 20, 41, 48, 61 and 69 post-induction, and serum levels of IL-17, IL-23, IL-27, IFN-y and TGF-ß were measured. Rats were sacrificed on the 69th day and thymus, lung, liver, spleen, kidney and hind paws were collected for histopathological examination
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.21.Ph.D.2014.El.E (Browse shelf(Opens below)) Not for loan 01010110067753000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.21.Ph.D.2014.El.E (Browse shelf(Opens below)) 67753.CD Not for loan 01020110067753000

Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Zoology

Rheumatoid arthritis (RA) is one of the major human systemic autoimmune diseases, affecting approximately 1% of the world population, with unknown etiology attacking synovial joints, causing bone erosion, which leads to joint deformation, fractures and severe disability. For which there is no effective cure available. CIA was chosen as an animal model of RA as it produces many of the clinical and pathological features of human RA. Male albino rats were divided into 7 groups: N, D, A, Cb, Ca, M and CM. Treatments in groups Ca, M and CM were initiated from day 20 and continued till day 69. Blood samples were collected on days 0, 20, 41, 48, 61 and 69 post-induction, and serum levels of IL-17, IL-23, IL-27, IFN-y and TGF-ß were measured. Rats were sacrificed on the 69th day and thymus, lung, liver, spleen, kidney and hind paws were collected for histopathological examination

Issued also as CD

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