Neuropharmacological evaluation of the possible effects of certain psychotropic and hepatotropic drugs in hepatic encephalopathy induced in rats / Marwa Ashour Masoud ; Supervised Sanaa A. Kenawy , Hanaa A. Mansour , Rania M. Abdelsalam
Material type:
- تقييم فارماكولوجى عصبى للتأثيرات المحتملة لبعض الأدوية النفسية والأدوية المؤثرة فى الكبد فى إعتلال المخ الكبدى المحدث فى الجرذان [Added title page title]
- Issued also as CD
Item type | Current library | Home library | Call number | Copy number | Status | Barcode | |
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قاعة الرسائل الجامعية - الدور الاول | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.08.09.Ph.D.2014.Ma.N (Browse shelf(Opens below)) | Not for loan | 01010110063367000 | ||
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مخـــزن الرســائل الجـــامعية - البدروم | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.08.09.Ph.D.2014.Ma.N (Browse shelf(Opens below)) | 63367.CD | Not for loan | 01020110063367000 |
Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology
The present study aimed to investigate the possible protective effects of certain hepatotropic drugs (neomycin and lactulose) and certain psychotropic drugs (fluoxetine and donepezil) in thioacetamide (TAA)-induced hepatic encephalopathy (HE) in rats. TAA (200mg/kg, p.o) was administered daily for two successive days at 24 hr interval to induce HE. Neomycin (540 mg/kg, p.o), lactulose (8 ml/kg, p.o), fluoxetine (10 mg/kg, p.o) or donepezil (10 mg/kg, p.o) were administered daily for seven successive days starting five days before TAA administration. The TAA group showed lower motor activity than the normal group by using open field and forced swimming tests
Issued also as CD
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