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Electromyographic evaluation of the role of bee venom in animal model of drug-induced myopathy / Mohammad Elsayed Elrefay Ghalwash ; Supervised Radwa Mahmoud Azmy , Eman Ahmed Maher , Basma Bahgat Elsayed

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Mohammad Elsayed Elrefay Ghalwash , 2018Description: 128 P. : charts , facsimiles ; 25cmOther title:
  • تقييم تأثير سم النحل على نموذج إعتلال العضلات فى حيوانات التجارب باستخدام رسم العضلات الكهربى [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine- Department of Neuro Physiology Summary: Objective: Statin-induced myopathy is the most common adverse effect of statins. It is a progressive autoimmune myopathy that persists despite drug discontinuation. Bee venom provides a potential means of reducing excessive immune response and sets a new alternative for control of inflammatory reaction. This study aimed at clarification of the role of bee venom in control or prevention of statin-induced myopathy using quantitative electromyography (QEMG) Methods: The present study was carried out on female 30 rats, randomly assigned into 3 groups: Control group, Statin group which received simvastatin 88 mg/kg/day for 2 weeks, and Venom group which was exposed to actual bee sting every other day for 2 weeks concurrent with simvastatin administration. QEMG of the quadriceps femoris and gastrocnemius muscles was performed. Measurements of serum CK and cholesterol levels and in addition to assessment of gastrocnemius muscle contractility were done
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.36.M.Sc.2018.Mo.E (Browse shelf(Opens below)) Not for loan 01010110077174000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.36.M.Sc.2018.Mo.E (Browse shelf(Opens below)) 77174.CD Not for loan 01020110077174000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine- Department of Neuro Physiology

Objective: Statin-induced myopathy is the most common adverse effect of statins. It is a progressive autoimmune myopathy that persists despite drug discontinuation. Bee venom provides a potential means of reducing excessive immune response and sets a new alternative for control of inflammatory reaction. This study aimed at clarification of the role of bee venom in control or prevention of statin-induced myopathy using quantitative electromyography (QEMG) Methods: The present study was carried out on female 30 rats, randomly assigned into 3 groups: Control group, Statin group which received simvastatin 88 mg/kg/day for 2 weeks, and Venom group which was exposed to actual bee sting every other day for 2 weeks concurrent with simvastatin administration. QEMG of the quadriceps femoris and gastrocnemius muscles was performed. Measurements of serum CK and cholesterol levels and in addition to assessment of gastrocnemius muscle contractility were done

Issued also as CD

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