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N{u2160}-linked metatonin dimers as bivalent ligands targeting dimeric melatonin receptors / Samy Abdalla Mehany Habib ; Supervsied Darius P. Zlotos

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Samy Abdalla Mehany Habib , 2014Description: 118 Leaves ; 30cmOther title:
  • كمركبات ثنائية التكافؤ تستهدف مستقبلات الميلاتونين المثنوية N{u2160}- مركبات ميلاتونين ثنائية الوحدات مرتبطة عن طريق [Added title page title]
Subject(s): Online resources: Dissertation note: Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceulical Chemistry Summary: The diverse physiological actions of the pineal neurohormone melatonin are mainly mediated through activation of two G-protein-coupled receptors MT₁, and MT₂. These receptors are known to form homo-and heterodimers with distinct functions and properties opening new perspectives for drug design and drug treatment. The bivalent ligand approach is a common strategy for targeting dimeric GPCRs
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Thesis Thesis قاعة الثقاقات الاجنبية - الدور الثالث المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.34.M.Sc.2014.Sa.N (Browse shelf(Opens below)) Not for loan 01010110072273000

Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceulical Chemistry

The diverse physiological actions of the pineal neurohormone melatonin are mainly mediated through activation of two G-protein-coupled receptors MT₁, and MT₂. These receptors are known to form homo-and heterodimers with distinct functions and properties opening new perspectives for drug design and drug treatment. The bivalent ligand approach is a common strategy for targeting dimeric GPCRs

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