Design synthesis and biological evaluation of novel tetrahydro - Ý - carboline derivatives as phosphodiesterase 5 inhibitors / Mohamed Saleh Mohamed Ali ; Supervised Ashraf H. Abadi
Material type:
TextLanguage: English Publication details: Cairo : Mohamed Saleh Mohamed Ali , 2009Description: 94 P. : facsimiles ; 30cmOther title: - تصميم وتشييد بعض مشتقات البيتاكربولين وتقييمها بيولوجيا كمثبطات لإنزيم الفسفودايستراز5 [Added title page title]
| Item type | Current library | Home library | Call number | Status | Barcode | |
|---|---|---|---|---|---|---|
Thesis
|
قاعة الثقاقات الاجنبية - الدور الثالث | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.34.M.Sc.2009.Mo.D (Browse shelf(Opens below)) | Not for loan | 01010110053006000 |
Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Science in Organic Chemistry
PDE5 inhibitors is a large class of compounds that are primarily used to treat erectile dysfunction (MED) as well as having other medical applications . Tadalafil is one of the most potent members among this class despite its efficacy in treatment of MED it only exhibits a modest selectivity of 5 - folds for PDE - 5 compareed PDE - 11 which may be involved in sperm formation motility and\ or other homonal functions
There are no comments on this title.
Click on an image to view it in the image viewer