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Effect of mithramycin and hydeoxyurea on fetal hemoglobin production in cultured erythroid cells from patients with B - thalassemia /

Ahmed Mohamed Ali

Effect of mithramycin and hydeoxyurea on fetal hemoglobin production in cultured erythroid cells from patients with B - thalassemia / تأثير الميثراميسين والهيدروكسى يوريا على تكوين الهيموجلوبين (اف) فى خلايا الدم الحمراء المزروعة من مرضى انيميا البحر الابيض المتوسط Ahmed Mohamed Ali ; Supervised Shahira Amin Zayed , Khaled Mohamed Salama , Rania Fawzy Hammoud - Cairo : Ahmed Mohamed Ali , 2008 - 115P. : charts ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty Of Medicine - Department Of Clinical and Chemical Pathology

The main issue of this study is to test whether mithramycin is able to augment HbF production in erythroid precursor cells from healthy human subjects as well as from B - thalassemia patients in comparison to hydroxyurea.This is a mandatory preliminary step in the evaluation of mithramycin as a potential drug for the development of treatment for these diseases



Cultured erythroid cells Fetal hemoglobin production Mithramycin and hydeoxyurea
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