Clinical significance of minimal residual disease in peripheral blood at day 8 induction in childhood precursor- B acute lymphoblastic leukemia / (Record no. 51858)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02882cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031254.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 150805s2014 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.19.05.Ph.D.2014.Se.C |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Seham Mohamed Mahmoud |
| 245 10 - TITLE STATEMENT | |
| Title | Clinical significance of minimal residual disease in peripheral blood at day 8 induction in childhood precursor- B acute lymphoblastic leukemia / |
| Statement of responsibility, etc. | Seham Mohamed Mahmoud ; Supervised Iman Abdelmokhles Sidhom , Magda Mahmoud Assem , Iman Aly Attia |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | الأهمية الاكلينيكية للمرض المتبقى الأدنى بخلايا الدم عند اليوم الثامن من مرحلة الحث للعلاج الكيميائى فى الأطفال الذين يعانون من اللوكيميا الليمفاوية الحادة-ذات الخلية (ب) المبكرة |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Seham Mohamed Mahmoud , |
| Date of publication, distribution, etc. | 2014 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 183 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Pediatric Oncology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Minimal residual disease (MRD) in childhood acute lymphoblastic leukemia (ALL) during the early stages of therapy is statistically significant indicator of outcome. Aim: To study the prognostic significance of MRD by flow-cytometry in peripheral blood (PB) on day-8 induction in pediatric B-precursor ALL. Patients and Methods: This is study included 140 newly diagnosed B-precursor ALL pediatric patients treated at the Children{u2019}s Cancer Hospital- Egypt during the period between mid of March 2010 and end of September 2011. ALL patients received adopted protocol of St. Jude Children{u2019}s Research Hospital total study XV for low or standard/high risk ALL. Results: The 3-year relapse-free survival (RFS) and event-free survival (EFS) were 87±3.5% and 82±3.7% respectively. Median follow up was 34.9 months (range 24{u2013}42). MRD PB day-8 <1% was encountered in 78% of patients. Patients with day-8 MRD <1% had 3-year RFS of 90.6±3.4% compared to 73±10.7% for day-8 MRD {u2265}1% (P=0.042). Prognostic factors had statistically significant impact on RFS by univariate analysis were patient risk, favorable triple trisomies, and MRD PB day-8. By multivariate analysis, patient risk was the only independent factor affecting RFS |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Acute lymphoblastic leukemia |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Favorable trisomies |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Minimal residual disease |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Iman Abdelmokhles Sidhom , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Iman Aly Attia , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Magda Mahmoud Assem , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Enas |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.19.05.Ph.D.2014.Se.C | 01010110066057000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.19.05.Ph.D.2014.Se.C | 01020110066057000 | 22.09.2023 | CD - Rom | 66057.CD |