Effect of stem cells and melatonin on amiodarone-treated thyroid gland in adult male albino rat: histological, histomorphometrical and immunohistochemical study / (Record no. 73552)

MARC details
000 -LEADER
fixed length control field 02886cam a2200349 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250223032348.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 190829s2019 ua dh f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level Ph.D
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.11.02.Ph.D.2019.Al.E
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Ali Ahmed Ali Kotb Mousa
245 10 - TITLE STATEMENT
Title Effect of stem cells and melatonin on amiodarone-treated thyroid gland in adult male albino rat: histological, histomorphometrical and immunohistochemical study /
Statement of responsibility, etc. Ali Ahmed Ali Kotb Mousa ; Supervised Soheir Hanafi Ahmed , Ehab Abdelaziz Ahmed Elshaarawy , Mogeda Mahdy Nasrallah
246 15 - VARYING FORM OF TITLE
Title proper/short title تأثير الخلايا الجذعية والميلاتونين علي الغدة الدرقية المعالجة بالأميودارون في ذكر الفار الأبيض البالغ: دراسة هستولوجية وهستومورفولوجية قياسية و هستوكيميائية مناعية
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Ali Ahmed Ali Kotb Mousa ,
Date of publication, distribution, etc. 2019
300 ## - PHYSICAL DESCRIPTION
Extent 129 P. :
Other physical details charts , facsimiles ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Anatomy
520 ## - SUMMARY, ETC.
Summary, etc. In the present study it was found that amiodarone administration in rats by gastric gavage tube resulted in changes in thyroid gland. These changes were in hormonal levels, histological and immunohistochemical changes. These changes were improved by treating rats with stem cells. Also, adding melatonin to the stem cells culture was found to have further beneficial effect. The present study was carried out to investigate the structural and functional changes in the thyroid gland following the administration of amiodarone, and to assess the possible role of stem cells and melatonin supplement in minimizing these changes in the gland of adult male albino rat as an animal model. On the other hand, malondialdehyde levels in thyroid tissue expressed a highly significant increase in groups III and IV compared to control group, while group V showed increased in only a significant manner than the control. Meanwhile, group IV and V showed statistically significant decrease from Group III. Also, group V decrease was insignificantly different from that of group IV. The PCR results showed highly significant increase of both IL-6 and VEGF in group III compared to the control one. Groups IV and V showed a highly significant decrease compared to group III
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Histomorphometrical
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Melatonin
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Thyroid Gland
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Ehab Abdelaziz Ahmed Elshaarawy ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Mogeda Mahdy Nasrallah ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Soheir Hanafi Ahmed ,
Relator term
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a>
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Asmaa
Reviser Cataloger
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.11.02.Ph.D.2019.Al.E 01010110078983000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.11.02.Ph.D.2019.Al.E 01020110078983000 22.09.2023 CD - Rom 78983.CD
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