Synthesis and anti tumor evaluation of Heterocyclic compounds synthesized from Ý-diketone and active methylene derivatives / Marwa Soliman Gaman Salama ; Supervised Rafat Milad Mohareb
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TextLanguage: English Publication details: Cairo : Marwa Soliman Gaman Salama , 2016Description: 120 P. ; 25cmOther title: - تحضير و قياس مضادات الأورام لمركبات غير متجانسة الحلقة محضرة من مشتقات البيتا ثنائى الكيتون و الميثيلين النشطة [Added title page title]
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Thesis
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قاعة الرسائل الجامعية - الدور الاول | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.12.10.M.Sc.2016.Ma.S (Browse shelf(Opens below)) | Not for loan | 01010110070999000 | ||
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مخـــزن الرســائل الجـــامعية - البدروم | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.12.10.M.Sc.2016.Ma.S (Browse shelf(Opens below)) | 70999.CD | Not for loan | 01020110070999000 |
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Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry
In this work the reaction of O-phenylenediamine (1) with diethylmalonate (2) in an oil bath at 120 {u00B0}C gave ethyl 2- (1H-benzo [d] imidazol-2-yl) acetate (3). Compound 3 was used in many acyclic and heterocyclic reactions. The latter products underwent a series of heterocyclization reactions to yield pyrazole, thiophene, pyridine and coumarin derivatives. The antitumor evaluations of the newly synthesized products against three cancer cell lines were measured
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