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Analytical study of some psychotropic drugs / Christine Maged Abdou Elmaraghy ; Supervised Sawsan Mohamed Mohamed Amer , Hesham Salem Sharaf Eldin , Marianne Nebsen Morcos

By: Contributor(s): Material type: TextLanguage: English Publication details: Cairo : Christine Maged Abdou Elmaraghy , 2015Description: 264 P. ; 25cmOther title:
  • دراسة تحليلية على بعض الأدوية النفسية [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry Summary: This thesis was to develop accurate,sensitive and validated spectrophotometric, chemometric, electrochemical, TLC- densitometric and HPLC methods for quantitative determination of three psychotropic drugs namely; Quetiapine fumarate in presence of its related compounds, Citalopram hydrobromide in presence of its degradation products and Clonazepam drug and Aripiprazole in presence of its degradation products. and simultaneous determination of Aripiprazole and co-administered Clonazepam in human plasma. The proposed methods were validated according to the ICH guidelines. The obtained results were statistically comparedwith those obtained from the reference HPLC method, showing no significant difference with respect to accuracy and precision
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Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.03.Ph.D.2015.Ch.A (Browse shelf(Opens below)) Not for loan 01010110069132000
CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.03.Ph.D.2015.Ch.A (Browse shelf(Opens below)) 69132.CD Not for loan 01020110069132000

Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry

This thesis was to develop accurate,sensitive and validated spectrophotometric, chemometric, electrochemical, TLC- densitometric and HPLC methods for quantitative determination of three psychotropic drugs namely; Quetiapine fumarate in presence of its related compounds, Citalopram hydrobromide in presence of its degradation products and Clonazepam drug and Aripiprazole in presence of its degradation products. and simultaneous determination of Aripiprazole and co-administered Clonazepam in human plasma. The proposed methods were validated according to the ICH guidelines. The obtained results were statistically comparedwith those obtained from the reference HPLC method, showing no significant difference with respect to accuracy and precision

Issued also as CD

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